Background: Catatonia is a neuropsychiatric syndrome characterized by motor, behavioral, and autonomic abnormalities. It is often underdiagnosed in geriatric patients with dementia despite established diagnostic criteria and treatment options. Objective: This systematic review investigates catatonia in the elderly, particularly those with dementia, to examine their clinical presentation, treatment response, and...
Apesar dos esforços e das medidas de prevenção e controlo que vêm sendo adotadas desde a década de 80 do século passado, o tabagismo continua a ser, em Portugal e no mundo, um dos mais importantes fatores evitáveis de doença crónica e de mortalidade prematura. 1 A carga da doença atribuível ao tabaco em Portugal foi estimada por Borges et al 2 há mais de uma década. Nesse estudo 11,7% das mortes em Portugal for...
OBJECTIVE: To study the effect of the satiety hormone, leptin, in saliva proteome and salivary gland histology and ultrastructure. DESIGN: Increases in blood leptin levels were induced through mini-pump infusion in male Wistar rats, during a period of 7 days. Saliva was collected before and at the end of the experimental period, for proteomic analysis, and major salivary glands were collected, at the end, for b...
Sweet taste plays a critical role in determining food preferences and choices. Similar to what happens for other oral sensations, individuals differ in their sensitivity for sweet taste and these inter-individual differences may be responsible for variations in food acceptance. Despite evidence that saliva plays a role in taste perception, this fluid has been mainly studied in the context of bitterness or astri...
6‐n‐propylthiouracil (PROP) is widely used in nutritional and health studies. However, only a limited number of studies have compared saliva composition between PROP taster phenotypes. The main aim of this work was to assess the relationship between saliva proteome and PROP responsiveness in young adults (N = 152) taking into account body mass index (BMI) and sex. SDS‐PAGE and 2‐DE protein profiles of saliva co...
Transthyretin amyloidosis is a conformational pathology characterized by the extracellular formation of amyloid deposits and the progressive impairment of the peripheral nervous system. Point mutations in this tetrameric plasma protein decrease its stability and are linked to disease onset and progression. Since non-mutated transthyretin also forms amyloid in systemic senile amyloidosis and some mutation bearer...
Objectivo: É fundamental os enfermeiros identificarem o tecido de hipergranulação e compreenderem o que pode traduzir em termos do ambiente biológico da ferida. É uma entidade comum nas feridas complexas, que se for gerida consegue-se controlar a cicatrização que se encontra estagnada. Com esta Revisão Sistemática da Literatura apoiada num estudo de caso, identificaram-se as intervenções de Enfermagem para a ge...