6 documents found, page 1 of 1
Recommendations for Vaccination in Adult Patients with Systemic Inflammatory Rh...
Cordeiro, I; Duarte, AC; Ferreira, J; Gonçalves, MJ; Meirinhos, T; Rocha, T; Romão, V; Sousa, S; Guedes, M; Conde, M; Abreu, C; Aleixo, MJ; Santos, MJSerious infections are a major cause of morbidity and mortality in systemic inflammatory rheumatic disease (SIRD) patients. Although vaccination may prevent numerous infections, vaccination uptake rates are low in this group of patients. OBJECTIVES: To develop evidence-based recommendations for vaccination in SIRD patients. METHODS: We searched MEDLINE (until 31 October 2014) and EMBASE (until 14 December 2014)...
The Portuguese Society of Rheumatology position paper on the use of biosimilars
Fonseca, JE; Gonçalves, J; Araújo, F; Cordeiro, I; Teixeira, F; Canhão, H; Pereira da Silva, JA; Garcês, S; Miranda, LC; Ramiro, Sofia; Roxo, AnaBiotechnological drugs have become a fundamental resource for the treatment of rheumatic patients. Patent expiry of some of these drugs created the opportunity for biopharmaceutical manufacturers to develop biosimilar drugs intended to be as efficacious as the originator product but with a lower cost to healthcare systems. Due to the complex manufacturing process and highly intricate structure of biologicals, a...
Ocurrencia simultánea de neurofibromatosis y esclerosis tuberosa, adquiridas co...
Janeiro, P; Cunha, M; Cordeiro, I; Santos, H; Antunes, NIntroducción. La neurofibromatosis tipo 1 y la esclerosis tuberosa son dos síndromes neurocutáneos distintos, resultado de la mutación de genes supresores tumorales, que aumentan la propensión a la génesis tumoral. Ambas tienen una herencia autosómica dominante y la mitad de los casos corresponden a nuevas mutaciones. Estas enfermedades raramente se presentan asociadas. Caso clínico. Niño sin antecedentes famil...
The effect of the woman's age, the rate of cleavage and embryo quality on obtai...
Cordeiro, I; Calhaz-Jorge, C; Barata, M; Leal, F; Proença, H; Coelho, A MMultiple factors influence the probability of obtaining a pregnancy through in vitro fertilization (IVF) and embryo transfer (ET). This retrospective study was designed to assess their importance in order to improve prognostic ability and treatment success. 341 consecutive embryo transfer cycles using the same ovarian stimulation protocol were considered and divided in two main groups: 92 cycles in which a clin...
Surface markers in B-cell neoplastic processes. I. Neoplasms with low density o...
Cordeiro, I; Novo, C M; Soares, V H; Graça, M F; Rocha, B
Marcadores de Superfície nos Processos Neoplásicos B.I - As Neoplasias Com Baix...
Cordeiro, I; Mendes Novo, C; Soares, VH; Graça, MF; Rocha, BDescrevem-se nove casos de processos neoplásicos de células B, com baixa densidade de Ig da membrana. Em todos estes casos se observa uma alta percentagem de MRFC e a presença de antigénios da classe II do MHC. Dos nove doentes apresentados, oito têm um quadro clínico e laboratorial típico de LLC e um tem um quadro compatível com uma LLC na sua fase inicial. A identificação dos isotipos da Ig de membrana sugere...