4 documents found, page 1 of 1
4SpecID: reference DNA libraries auditing and annotation system for forensic ap...
Neto, Luís; Pinto, Nádia; Proença, Alberto José; Amorim, António; Conde-Sousa, EduardoForensic genetics is a fast-growing field that frequently requires DNA-based taxonomy, namely, when evidence are parts of specimens, often highly processed in food, potions, or ointments. Reference DNA-sequences libraries, such as BOLD or GenBank, are imperative tools for taxonomic assignment, particularly when morphology is inadequate for classification. The auditing and curation of these datasets require reli...
Population analysis and evolution of Saccharomyces cerevisiae mitogenomes
Vieira, Daniel; Esteves, Soraia; Santiago, Carolina; Conde-Sousa, Eduardo; Fernandes, Ticiana; Pais, Célia; Soares, Pedro; Franco-Duarte, RicardoThe study of mitogenomes allows the unraveling of some paths of yeast evolution that are often not exposed when analyzing the nuclear genome. Although both nuclear and mitochondrial genomes are known to determine phenotypic diversity and fitness, no concordance has yet established between the two, mainly regarding strains’ technological uses and/or geographical distribution. In the current work, we proposed a n...
A dispersal of Homo sapiens from southern to eastern Africa immediately precede...
Rito, Teresa S; Vieira, Daniel; Silva, Marina; Conde-Sousa, Eduardo; Pereira, Luísa; Mellars, Paul; Richards, Martin B.; Soares, PedroAfrica was the birth-place of Homo sapiens and has the earliest evidence for symbolic behaviour and complex technologies. The best-attested early flowering of these distinctive features was in a glacial refuge zone on the southern coast 100-70 ka, with fewer indications in eastern Africa until after 70 ka. Yet it was eastern Africa, not the south, that witnessed the first major demographic expansion, ~70-60 ka,...
Mitogenome diversity in Sardinians: a genetic window onto an island's past
Olivieri, Anna; Sidore, Carlo; Achilli, Alessandro; Angius, Andrea; Posth, Cosimo; Furtwängler, Anja; Brandini, Stefania; Capodiferro, Marco RosarioSardinians are "outliers" in the European genetic landscape and, according to paleogenomic nuclear data, the closest to early European Neolithic farmers. To learn more about their genetic ancestry, we analyzed 3,491 modern and 21 ancient mitogenomes from Sardinia. We observed that 78.4% of modern mitogenomes cluster into 89 haplogroups that most likely arose in situ. For each Sardinian-specific haplogroup (SSH)...