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BACA: um arquivo vivo para a conservação da biodiversidade microbiana dos Açores

Luz, R.; Cordeiro, R.; Fonseca, A.; Gonçalves, V.

BACA é o acrónimo do Banco de Algas e Cianobactérias dos Açores, uma coleção de culturas fundada em 2018 na Universidade dos Açores e associada ao Centro de Investigação em Biodiversidade e Recursos Genéticos, Polo Açores, da Universidade dos Açores (CIBIO-Açores). Esta coleção compreende mais de 800 culturas de microrganismos fotossintéticos (Figura 1), nomeadamente microalgas e cianobactérias, oriundas de tod...


Monkeypox virus infection in HIV-1- coinfected patients previously vaccinated a...

Brazão, C.; Garrido, P.M.; Alpalhão, M.; Roda, A.; Vieitez-Frade, J.; Ferreira, J.A.; Pelerito, A.; Lopes de Carvalho, I.; Cordeiro, R.; Borrego, M.J.

Monkeypox is a zoonotic orthopoxvirus that incidentally causes disease in humans similar to smallpox, although with lower mortality. This virus is endemic to western and central Africa, with outbreaks in occidental countries related to exotic pet trade and international travel. Coincident immunity to monkeypox virus was previously achieved with vaccinia virus vaccination; however, eradicating smallpox and subse...


Outbreak of monkeypox in an STD clinic in Lisbon

Caldeira, M.; Fernandes, C.; Neves, J.; João, A.; Calado, R.; Pinto, A.R.; Borrego, M.J.; Cordeiro, R.; Machado, J.; Pelerito, A.; Lopes de Carvalho, I.

We present the preliminary results of the first 43 patients with a definitive diagnosis of human infection with monkeypox virus, from the dermatovenereology department of Hospital Santo António dos Capuchos, Lisbon, in May 2022 [...].


Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022

Duque, M.P.; Ribeiro, S.; Martins, J.V.; Casaca, P.; Leite, P. P.; Tavares, M.; Mansinho, K.; Duque, L.M.; Fernandes, C.; Cordeiro, R.; Borrego, M.J.

Up to 27 May 2022, Portugal has detected 96 confirmed cases of monkeypox. We describe 27 confirmed cases (median age: 33 years (range: 22–51); all males), with an earliest symptom onset date of 29 April. Almost all cases (n = 25) live in the Lisbon and Tagus Valley health region. Most cases were neither part of identified transmission chains, nor linked to travel or had contact with symptomatic persons or with ...


Cyanobacteria phylogenetic studies reveal evidence for polyphyletic genera from...

Cordeiro, R.; Luz, R.; Vasconcelos, V.; Gonçalves, V.; Fonseca, A.

Cyanobacteria are among the most diverse morphological microorganisms that inhabit a great variety of habitats. Their presence in the Azores, a volcanic archipelago of nine islands in the middle of the North Atlantic Ocean, has already been reported. However, due to the high diversity of cyanobacteria habitats, their biodiversity is still understudied, mainly in extreme environments. To address this, a total of...


Paralytic Shellfish Poisoning due to ingestion of contaminated mussels: a case r...

Ribeiro, I.; Pelerito, A.; Cordeiro, R.; Vale, P.; Núncio, M.S.; Lopes de Carvalho, I.

In Portugal, the potent paralytic shellfish toxins (PSTs) have appeared irregularly since the onset of a national monitoring program for marine biotoxins in 1986. In years where high contamination levels were attained in bivalves, sporadic cases of human poisonings have been recorded, as in 1994 and 2007. The reappearance of high contamination levels led to the appearance of new cases during the autumn of 2018....


Paralytic shellfish poisoning due to ingestion of contaminated mussels: a 2018 ...

Lopes de Carvalho, I.; Pelerito, A.; Ribeiro, I.; Cordeiro, R.; Núncio, M.S.; Vale, P.

In Portugal, the potent paralytic shellfish toxins (PSTs) have appeared irregularly since the onset of a national monitoring program for marine biotoxins in 1986. In years where high contamination levels were attained in bivalves, sporadic cases of human poisonings have been recorded, as in 1994 and 2007. The reappearance of high contamination levels led to the appearance of new cases during the autumn of 2018....


Vacinação anti-raiva em humanos: a importância de avaliar a eficácia da vacinaç...

Cordeiro, R.; Almeida Santos, J.; Pelerito, A.; Lopes de Carvalho, I.; Núncio, M.S.

A raiva (RABV) é uma doença zoonótica causada pelo vírus do género Lyssavirus. Tanto a RABV animal como a humana são evitáveis pela vacinação. A vacinação préexposição é indicada a indivíduos que viajem para áreas geográficas de risco, para profissionais que manipulem o vírus ou que tenham contacto com animais potencialmente infetados. O esquema de vacinação pré-exposição inclui três doses. No entanto, caso se ...


Biological toxins detection: a rapid diagnosis in an emergency response

Lopes de Carvalho, I.; Cordeiro, R.; Saraiva, M.; Cunha, I.C.; Pelerito, A.; Núncio, M.S.

Toxins are chemical substances of biological origin, and they can be considered chemical or biological warfare agents. Four toxins are included in the list of bioterrorism agents: botulinum toxin (BoNT), saxitocin, ricin, and staphylococcal enterotoxin B. BoNT is included in Category A, while the other 3 are considered Category B. Botulism is a potentially fatal disease caused solely by the action of serologica...


CYP2D6 and IL-6 c-174G variants in schistosomiasis haematobia

Cordeiro, R.; Alves, H.; Bordalo, A.; Richter, J; Botelho, M.C.

AIM: To study the polymorphic variants in CYP2D6 and the C-174G promoter polymorphism of the IL-6 gene on S. haematobium infected patients from an endemic area of Guinea Bissau. BACKGROUND: - Our group has shown that schistosome egg associated catechol estrogens induce tumor-like phenotypes in urothelial cells. These estrogen metabolites might also be the cause of schistosomiasis associated infertility; - The c...


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