2 documents found, page 1 of 1
Synthesis and antifungal activity In vitro of isoniazid derivatives against his...
Cordeiro, Rossana de Aguiar; Marques, Francisca Jakelyne de Farias; Cordeiro, Rebecca de Aguiar; Silva, Marcos Reinaldo daHistoplasmosis is a severe infection that affects millions of patients worldwide and is endemic in the Americas. Amphotericin B (AMB) and itraconazole are highly effective for the treatment of severe and milder forms of the disease, but AMB is toxic, and the bioavailability of itraconazole is erratic. Therefore, it is important to investigate new classes of drugs for histoplasmosis treatment. In this study, a s...
Coccidioides posadasii infection in bats, Brazil
Marques, Francisca Jakelyne de Farias; Cordeiro, Rossana de Aguiar; Silva, Kylvia Rocha de Castro e; Brilhante, Raimunda Sâmia NogueiraStudies have demonstrated that bats (order Chiroptera) are reservoirs for many infectious agents, including protozoa, bacteria, viruses, and fungi (1). Several studies confi rm that bats have a great effect on human health because they can transmit numerous infectious agents and provide a reservoir for emerging pathogens (1,2). The interaction between these animals and pathogenic fungi is well illustrated by th...