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Osimertinib-induced cutaneous vasculitis: A case report and review of the liter...
Hilário Soldin, Inês; Barros Alves, Filipa; Cordeiro e Cunha, Joana; Santos, Joana; Estevinho, FernandaA 77-year-old patient with a history of stage IVa (cT4N3M1a) lung adenocarcinoma, treated with osimertinib 80 mg/day, developed palpable purpura nine days after starting therapy. Skin biopsy revealed leukocytoclastic vasculitis. A complete clinical and lab workup for systemic involvement was unremarkable. The patient suspended osimertinib and started on methylprednisone 1mg/Kg/day. Skin lesions gradually improv...
Date: 2024
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Origin: THORAC (Thoracic Cancer Journal)