6 documents found, page 1 of 1
Urogenital tuberculosis in a patient with end-stage renal disease
Almeida,André Patrício Ferreira de; Silva,Dina Fabrício da; Petruccelli,Karla Cristina Silva; Matos,Juliana da Costa; Moreira,Rodrigo XavierAbstract Tuberculosis is one of the most common infections worldwide with particularly high incidence rates in countries with unfavorable socioeconomic conditions and among persons with impaired immune systems. While most patients with this disease will present with pulmonary tuberculosis, immunocompromised individuals also commonly present with extrapulmonary manifestations. We report the case of a 28-year-old...
Ascaris lumbricoides coinfection reduces tissue damage by decreasing IL-6 level...
Santos,João Hugo Abdalla; Bührer-Sékula,Samira; Melo,Gisely Cardoso; Cordeiro-Santos,Marcelo; Pimentel,João Paulo Diniz; Gomes-Silva,AdrianoAbstract INTRODUCTION: Immunological control of Mycobacterium tuberculosis infection is dependent on the cellular immune response, mediated predominantly by Th1 type CD4+ T cells. Polarization of the immune response to Th2 can inhibit the host immune protection against pathogens. Patients with tuberculosis coinfected with helminths demonstrate more severe pulmonary symptoms, a deficiency in the immune response ...
Tuberculosis: renewed challenge in Brazil
Kritski,Afranio; Andrade,Kleydson Bonfim; Galliez,Rafael Mello; Maciel,Ethel Leonor Noia; Cordeiro-Santos,Marcelo; Miranda,Silvana SpindolaAbstract This article reviews tuberculosis control actions performed over the last decade, at a global level. The perspectives for the fulfillment of the goals of the new Global Tuberculosis Elimination Plan are described, where the insertion of social protection (Pillar 2) and research (Pillar 3) will play an innovative and strategic role, especially in high-burden countries, like Brazil.
Predictors of mortality among intensive care unit patients coinfected with tube...
Ferreira,Marcia Danielle; Neves,Cynthia Pessoa das; Souza,Alexandra Brito de; Beraldi-Magalhães,Francisco; Migliori,Giovanni BattistaABSTRACT Objective: To identify factors predictive of mortality in patients admitted to the ICU with tuberculosis (TB)/HIV coinfection in the Manaus, Amazon Region. Methods: This was a retrospective cohort study of TB/HIV coinfected patients over 18 years of age who were admitted to an ICU in the city of Manaus, Brazil, between January of 2011 and December of 2014. Sociodemographic, clinical, and laboratory var...
Temporal distribution of tuberculosis in the State of Amazonas, Brazil
Garrido,Marlucia da Silva; Bührer-Sékula,Samira; Souza,Alexandra Brito de; Ramasawmy,Rajendranath; Quincó,Patrícia de Lima; Monte,Rossicleia LinsTuberculosis (TB) is one of the infectious diseases that contributes most to the morbidity and mortality of millions of people worldwide. Brazil is one of 22 countries that accounts for 80% of the tuberculosis global burden. The highest incidence rates in Brazil occur in the States of Amazonas and Rio de Janeiro. The aim of this study was to describe the temporal distribution of TB in the State of Amazonas. Bet...
Extra-pulmonary manifestations of paracoccidioidomycosis associated with acquir...
Safe,Izabella Picinin; Valle,Fabio Francesconi do; Maia,Daniela Cristina Caetano; Agonio,Barbara; Monte,Rossicleia Lins; Araujo,Jose de RibamarWe present a patient with Paracoccidioidomycosis/HIV coinfection which has been investigated because of chronic monoarthritis and mucocutaneous lesions. A biopsy of the synovial membrane and skin revealed structures consistent with Paracoccidioides brasiliensis. At diagnosis, the count of CD4 + T cells was 44 cells/mm3. We emphasize the importance of clinical suspicion of Paracoccidioidomycosis in patients with...