Quality management and independent assessment of high-throughput sequencing-based virus diagnostics have not yet been established as a mandatory approach for ensuring comparable results. The sensitivity and specificity of viral high-throughput sequence data analysis are highly affected by bioinformatics processing using publicly available and custom tools and databases and thus differ widely between individuals...
University of Bonn Medical Centre. Institute of Virology. Bonn, Germany / Federal University of Bahia. University Hospital Prof. Edgard Santos. Infectious Diseases Research Laboratory. Salvador BA, Brazil.; Justus Liebig University. Institute of Medical Virology. National Reference Center for Hepatitis B and D Viruses. Giessen, Germany / German Centre for Infection Research. Germany.; University of Bonn Medical...
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