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Efficacy of molecular and nano-therapies on brain tumor models in microfluidic ...

Martins, Ana M.; Brito, Alexandra; Barbato, Maria Grazia; Felici, Alessia; Reis, R. L.; Pires, R. A.; Pashkuleva, I.; Decuzzi, Paolo

The three-dimensional (3D) organization of cells affects their mobility, proliferation, and overall response to treatment. Spheroids, organoids, and microfluidic chips are used in cancer research to reproduce in vitro the complex and dynamic malignant microenvironment. Herein, single-and double-channel microfluidic devices are used to mimic the spatial organization of brain tumors and investigate the therapeuti...

Date: 2023   |   Origin: RepositóriUM - Universidade do Minho
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