48 documents found, page 1 of 5
A New World disease: Dual diagnostic challenges in travelers returning from Cos...
Brazão, Cláudia; Borges-Costa, João; Antunes-Duarte, Sofia; Mancha, Dora; Sun, Lanyu; Marques, Tiago; Gargaté, Maria João; Vilares, Anabela; Reis, TâniaCutaneous diseases in returning travelers encompass a wide spectrum of etiologies and often pose diagnostic challenges. We present the cases of a 50-year-old man and a 57-year-old woman who presented with a 3-month history of erythematous, ulcerated plaques with well-defined elevated borders and a necrotic center on the lower limbs that began 3 weeks after returning from vacation in Costa Rica. Cutaneous biopsy...
Guidelines for the Diagnosis and Treatment of Uncomplicated (Non-Lymphogranulom...
Andrade, Pedro; Azevedo, Jacinta; Lisboa, Carmen; Fernandes, Cândida; Borrego, Maria José; Borges-Costa, João; Reis, Joel; Santiago, FelicidadeChlamydia trachomatis infection is the most prevalent sexually transmitted bacterial infection in the world. Being associated with a large number of asymptomatic carriers, the diagnosis is frequently challenging and requires appropriate laboratory testing. In Portugal, the incidence of the disease has been consistently increasing in recent years, meaning that special awareness is required for case identificatio...
M. genitalium detection through multiplex real-time PCR assay: three-year study...
Palmeiro, A. G.; Antunes Duarte, Sofia; Barreto, M. R.; Borges-Costa, JoãoThe recent availability of multiplex nucleic acid amplification tests (NAATS) allows for the identification of M. genitalium, an increasingly important bacterium with rising antibiotic resistances.1–3 The authors present data with laboratory confirmation of M. genitalium infections within the first 3 years (from January 2019 to December 2021) when this test was already available in Centro Hospitalar Lisboa Nort...
Imiquimod in association with Valacyclovir for refractory verrucous perianal He...
Antunes Duarte, Sofia; Pinto, Ana; Soares-de-Almeida, Luís; Borges-Costa, JoãoGenital herpes is a sexually transmitted disease with a high global prevalence mainly caused by herpes simplex virus (HSV) type 2, although there has been an increase in the number of cases caused by HSV-1 in recent years. Coinfection by HSV is common in patients with the human immunodeficiency virus (HIV). The atypical clinical presentations of HSV infection are rare, but they are now more frequent in clinical...
Two cases of Darier disease efficiently treated with combination of oral retino...
Garrido, Pedro; Queirós, Catarina; Soares-de-Almeida, Luís; Borges-Costa, JoãoDarier disease (DD) is an uncommon autosomal dominant genodermatosis caused by mutations of the ATP2A2 gene, which encodes the sarcoplasmic/endoplasmic reticulum calcium-ATPase isoform 2 (SERCA2). Disfunction of this pump disturbs intracellular Ca2+ signaling, compromising keratinocyte differentiation and intercellular adhesion. Although many therapeutic modalities have been investigated, treatment of DD remain...
Monkeypox infection and bacterial cellulitis: a complication to look for
De Sousa, Diogo; Vieitez Frade, Joana; Patrocínio, João; Borges-Costa, João; Filipe, PauloHuman monkeypox (MPX) is an endemic zoonotic disease in regions of Africa caused by the monkeypox virus, with recent outbreaks in several non-African countries. In this study, we present two cases of patients with MPX infection complicated by a deep skin infection. Both patients presented to our dermatology clinic with a clinical syndrome characteristic of MPX. The diagnosis was confirmed based on swabs of skin...
Human monkeypox coinfection with acute HIV: an exuberant presentation
De Sousa, Diogo; Patrocínio, João; Vieitez Frade, Joana; Correia, Catarina; Borges-Costa, João; Filipe, PauloHuman monkeypox (MPX) is a zoonotic endemic disease in regions of Africa caused by the monkeypox virus, with a recent outbreak in several non-African countries. We report a case of a 24-year-old male patient with a concurrent diagnosis of MPX and acute HIV infection who presented to our Emergency Care Dermatology Clinic with disseminated papules throughout the trunk, face and genital area. On the perianal area,...
Male Urethritis Caused by Trichomonas vaginalis
Roda, Ângela; Borges-Costa, JoãoTrichomoniasis is one of the most common sexually transmitted infections worldwide. In women, Trichomonas vaginalis infection may present with vaginitis, cervicitis, or pelvic inflammatory disease, while in men it is mainly asymptomatic or causes mild and transient symptoms of urethritis, epididymitis, or prostatitis. In the past, little importance had been given to the impact of T. vaginalis infection on men’s...
A unique presentation of papulonodular secondary syphilis in an elderly patient
Correia, Catarina; Mendes, Rita; Mendonça-Sanches, Maria; Fernandes, Sonia; Soares-de-Almeida, Luís; Borges-Costa, João; Filipe, PauloAn 83‐year‐old female was observed for a 1‐week history of asymptomatic cutaneous papules and nodules on both legs, also reporting weight loss in the previous months, which she was unable to quantify, with no additional systemic symptoms.
Urogenital Trichomonas vaginalis infection in males: a case report and retrospe...
Alpalhão, Miguel; Marques Lito, Luís; Filipe, Paulo; Borges-Costa, JoãoWe report the case of a 31-year-old male who presented to our Venereology Department with dysuria and a 2-year history of a minimal clear urethral discharge. He had been treated with multiple courses of antibiotics, namely, intramuscular ceftriaxone, azithromycin, ciprofloxacin, and doxycycline, even though laboratorial tests for Neisseria gonorrhoeae and Chlamydia trachomatis were consistently negative. The pa...