Background: The aim of the present study is to analyze subjective happiness in relation to leisure time in 10-year-old boys and girls from Brazil, Chile and Spain and to determine which leisure time activity has a greater effect on their subjective happiness and whether there are differences according to gender. (2) Methods: Data from the third wave of the Children's Worlds Project was used, which was collected...
Qual a associação entre empatia, regulação parental e violência em adolescentes. Este estudo analisa a associação entre empatia, regulação parental e violência em adolescentes. Estudo transversal realizado com 722 adolescentes de Foz do Iguaçu. A coleta de dados foi realizada por meio de um questionário. Estatística descritiva, teste do qui-quadrado e regressão logística binomial foram utilizados para análise d...
Foam cells are specialized lipid-loaded macrophages derived from monocytes and are a key pathological feature of atherosclerotic lesions. Lysophosphatidylcholine (LPC) is a major lipid component of the plasma membrane with a broad spectrum of proinflammatory activities and plays a key role in atherosclerosis. However, the role of LPC in lipid droplet (LD) biogenesis and the modulation of inflammasome activation...
Tese (doutorado)—Universidade de Brasília, Instituto de Ciências Biológicas, Departamento de Biologia Celular, Programa de Pós-Graduação em Biologia Molecular, 2020.; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).; O vírus Zika (ZIKV), um arbovírus da família Flaviviridae, causou recentemente um surto no Brasil e levou ao desenvolvimento de desordens neurológicas pós-infecção, tais como m...
Zika virus (ZIKV) has a strong tropism for the nervous system and has been related to post-infection neurological syndromes. Once neuronal cells are infected, the virus is capable of modulating cell metabolism, leading to neurotoxicity and cellular death. The negative efect of ZIKV in neuron cells has been characterized. However, the description of molecules capable of reversing these cytotoxic efects is still ...
Inflammation has been known as one of the main keys to the establishment and progression of cancers. Chronic low-grade inflammation is also a strategic condition that underlies the causes and development of metabolic syndrome and obesity. Moreover, obesity has been largely related to poor prognosis of tumors by modulating tumor microenvironment with secretion of several inflammatory mediators by tumor-associate...
This paper presents an innovative approach to coordinate typical protection devices of transmission, subtransmission and distribution systems – fuse links and functions ANSI 21, 67, 87, 50 and 51. The settings obtained by the optimization process are the following: characteristic curve, time dial and pickup current settings of overcurrent functions; delay of zones 2 and 3 of distance functions; and the rated cu...
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Deubiquitinating enzymes (DUBs) play an important role in regulating a variety of eukaryotic processes. In this context, exploring the role of deubiquitination in Leishmania infantum could be a promising alternative to search new therapeutic targets for leishmaniasis. Here we present the first characterization of a DUB from L. infantum, otubain (OtuLi), and its localization within parasite. The recombinant OtuL...
Orientador : Prof. Dr. Carlos Eduardo Pianovski Ruzyk; Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Jurídicas, Programa de Pós-Graduação em Direito. Defesa: Curitiba, 2016; Inclui referências : f. 154-160; Resumo: A presente dissertação tem como desígnio ponderar sobre a proteção de dados pessoais a partir da concepção da privacidade como autodeterminação informativa, perquirindo s...