3 documents found, page 1 of 1
Metabolic Disruption of Gold Nanospheres, Nanostars and Nanorods in Human Metas...
Soares, Sílvia; Pereira, Cláudia; Sousa, André P; Oliveira, Ana Catarina; Sales, M. Goreti F.; Correa-Duarte, Miguel A; Guerreiro, Susana GNanomaterials offer a broad spectrum of applications in biomedicine. The shapes of gold nanoparticles could modulate tumor cell behavior. Spherical (AuNPsp), stars (AuNPst) and rods (AuNPr) shapes of polyethylene glycol coated-gold nanoparticles (AuNPs-PEG) were synthesized. Metabolic activity, cellular proliferation, and reactive oxygen species (ROS) were measured and the impact of AuNPs-PEG in metabolic enzym...
The Influence of miRNAs on Radiotherapy Treatment in Prostate Cancer - A System...
Soares, Sílvia; Guerreiro, Susana G; Cruz-Martins, Natália; Faria, Isabel; Baylina, Pilar; Sales, Maria Goreti; Correa-Duarte, Miguel AIn the last years, extensive investigation on miRNomics have shown to have great advantages in cancer personalized medicine regarding diagnosis, treatment and even clinical outcomes. Prostate cancer (PCa) is the second most common male cancer and about 50% of all PCa patients received radiotherapy (RT), despite some of them develop radioresistance. Here, we aim to provide an overview on the mechanisms of miRNA ...
Impact of citrate and lipid-functionalized magnetic nanoparticles in dehydropep...
Veloso, Sérgio R S; Silva, Joana F G; Hilliou, L.; Moura, Cacilda; Coutinho, Paulo J. G.; Martins, J. A. R.; Testa-Anta, Martín; Salgueiriño, VerónicaCurrently, the nanoparticle functionalization effect on supramolecular peptide-based hydrogels remains undescribed, but is expected to affect the hydrogels' self-assembly and final magnetic gel properties. Herein, two different functionalized nanoparticles: citrate-stabilized (14.4 ± 2.6 nm) and lipid-coated (8.9 ± 2.1 nm) magnetic nanoparticles, were used for the formation of dehydropeptide-based supramolecula...