2 documents found, page 1 of 1
International clinical guidelines for the management of phosphomannomutase 2-co...
Altassan, Ruqaiah; Péanne, Romain; Jaeken, Jaak; Barone, Rita; Bidet, Muad; Borgel, Delphine; Brasil, Sandra; Cassiman, David; Cechova, AnnaWe would like to thank the Metabolic ERN (MetabERN) for their support to our study.; Phosphomannomutase 2 (PMM2-CDG) is the most common congenital disorder of N-glycosylation and is caused by a deficient PMM2 activity. The clinical presentation and the onset of PMM2-CDG vary among affected individuals ranging from a severe antenatal presentation with multisystem involvement to mild adulthood presentation limite...
Stability Improvements in a Rail-to-Rail Input/Output, Constant Gm Operational ...
Correia, Joana; Mancelos, Nuno; Goes, JoãoThe use of the dynamic threshold MOS (DTMOS) technique is evaluated in a two-stage rail-to-rail Input/Output, constant G m amplifier. The proper choice of specific transistors in which the technique should be used is presented, as well as the resulting improvements, mainly regarding stability of the circuit at low voltage operation. The DTMOS technique is used in the NMOS transistors of the folded-cascode input...