93 documents found, page 1 of 10
Efeitos de um Programa de Fisioterapia Aquática no Risco de Queda em Doentes co...
Cristóvão, A; Correia, A; Rebelo, PIntrodução e Objetivos – Aproximadamente 80% dos sobreviventes de acidente vascular cerebral (AVC) apresentam défices de equilíbrio e até 58% apresentam risco de queda no primeiro ano após AVC. Uma das intervenções que tem sido utilizada para o tratamento desta sequela é a fisioterapia aquática. O objetivo deste trabalho é identificar os efeitos de um plano de fisioterapia aquática em grupo no risco de queda, e...
Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, again...
Seabra, R; Malhão, F; Correia, A; Costa, C; Kijjoa, A; Rocha, ETriple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer (BC) with a typically poorer prognosis than other subtypes of BC and limited therapeutic options. Therefore, new drugs would be particularly welcome to help treat TNBC. Preussin, isolated from the marine sponge-associated fungus, Aspergillus candidus, has shown the potential to reduce cell viability and proliferation as well ...
Mannosylated glycans impair normal T-cell development by reprogramming commitme...
Vicente, MM; Alves, I; Fernandes, Â; Dias, AM; Santos-Pereira, B; Pérez-Anton, E; Santos, S; Yang, T; Correia, A; Münster-Kühnel, A; Almeida, ARMT-cell development ensures the formation of diverse repertoires of T-cell receptors (TCRs) that recognize a variety of antigens. Glycosylation is a major posttranslational modification present in virtually all cells, including T-lymphocytes, that regulates activity/functions. Although these structures are known to be involved in TCR-selection in DP thymocytes, it is unclear how glycans regulate other thymic dev...
Assessing the Risk for Falls Among Portuguese Community-Dwelling Stroke Survivo...
Pimenta, C; Correia, A; Alves, M; Virella, DPurpose: This study assesses the estimation of the risk for falls among community-dwelling stroke survivors referred for ambulatory physiotherapy and explores factors that affect the risk. Methods: Observational, cross-sectional with nested case-control study, of individuals, referred to physiotherapy less than 12 months after stroke and able to walk independently. Berg Balance Scale, Timed Up and Go Test, and ...
A Realidade da Fisioterapia Vestibular em Portugal: Análise Preliminar
Benzinho, T; Correia, A; Azevedo, AP; Costa, C; Jordão, J; Cabral, MA; Póvoa, RIntrodução: A Reabilitação Vestibular (RV) é uma abordagem terapêutica dirigida aos sinais e sintomas causados por disfunção vestibular, com o objetivo de acelerar o processo natural de compensação baseada nos mecanismos centrais de neuroplasticidade. Visando maximizar a autonomia e independência funcional, os fisioterapeutas integraram as equipas com os primeiros exercícios descritos em 1940 por Cawthorne & Co...
Clinical performance of monolithic CAD/CAM tooth-supported zirconia restoration...
Leitão, CB; Fernandes, GO; Azevedo, LP; Araújo, FM; Donato, H; Correia, APurpose: The purpose of this systematic review was to evaluate the survival rate, biological complications, technical complications, and clinical behavior of single crowns supported by teeth made up in monolithic zirconia with CAD/CAM technology. Study selection: An extensive electronic search was conducted through Medline/PubMed, Embase, and Cochrane Library databases. Additional manual search was performed on...
Better Balance: a Randomised Controlled Trial of Oculomotor and Gaze Stability ...
Correia, A; Pimenta, C; Alves, M; Virella, DObjective: To assess the effect of a domiciliary program of oculomotor and gaze stability exercises on the incidence of falls and risk of fall in stroke survivors. Design: Two-arm, non-blinded parallel randomized controlled trial. Subjects: Stroke survivors older than 60 years, with positive Romberg test and autonomous gait after the stroke. Setting: Physiotherapy outpatient clinic of a tertiary care hospital. ...
Dectin-1-Mediated Production of Pro-Inflammatory Cytokines Induced by Yeast β-G...
Pedro, ARV; Lima, T; Fróis-Martins, R; Leal, B; Ramos, IC; Martins, EG; Cabrita, ARJ; Fonseca, AJM; Maia, MRG; Vilanova, M; Correia, AYeast-derived products containing β-glucans have long been used as feed supplements in domesticated animals in an attempt to increase immunity. β-glucans are mainly recognized by the cell surface receptor CLEC7A, also designated Dectin-1. Although the immune mechanisms elicited through Dectin-1 activation have been studied in detail in mice and humans, they are poorly understood in other species. Here, we evalu...
Vaccines in Congenital Toxoplasmosis: Advances and Perspectives
Barros, M; Teixeira, D; Vilanova, M; Correia, A; Teixeira, N; Borges, MCongenital toxoplasmosis has a high impact on human disease worldwide, inducing serious consequences from fetus to adulthood. Despite this, there are currently no human vaccines available to prevent this infection. Most vaccination studies against Toxoplasma gondii infection used animal models in which the infection was established by exogenous inoculation. Here, we review recent research on potential T. gondii...
Siderophore-Mediated Iron Acquisition Plays a Critical Role in Biofilm Formatio...
Oliveira, F; Lima, T; Correia, A; Silva, AM; Soares, C; Morais, S; Weißelberg, S; Vilanova, M; Rohde, H; Cerca, NIron acquisition through siderophores, a class of small, potent iron-chelating organic molecules, is a widely spread strategy among pathogens to survive in the iron-restricted environment found in the host. Although these molecules have been implicated in the pathogenesis of several species, there is currently no comprehensive study addressing siderophore production in Staphylococcus epidermidis. Staphylococcus...