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The Cardiometabolic Impact of Rebaudioside A Exposure during the Reproductive S...

Bracchi, I; Morais, J; Coelho, JA; Ferreira, AF; Alves, I; Mendes, C; Correia, B; Gonçalves, A; Guimarães, JT; Pires, IF; Keating, E; Negrão, R

The consumption of non-sugar sweeteners (NSS) has increased during pregnancy. The European Food Safety Agency suggested that steviol glycosides, such as Rebaudioside A (RebA), the major sweetener component of stevia, are safe for humans up to a dose of 4 mg/kg body weight/day. However, the World Health Organization recommended in 2023 the restraint of using NSS, including stevia, at any life stage, highlighting...


Improvement of Mineral and Bone Disorders After Renal Transplantation

Ferreira, AC; Mendes, M; Silva, C; Cotovio, P; Aires, I; Navarro, D; Caeiro, F; Ramos, R; Salvador, R; Correia, B; Cabral, G; Nolasco, F; Ferreira, A

Background: Posttransplant mineral and bone diseases are causes of fractures, and their association with cardiovascular events is being studied. Methods: We analyzed the evolution of biochemical, histological, and imaging parameters pre- and 1 y post-renal transplantation in 69 patients and correlated mineral and bone findings with coronary calcifications. At inclusion and after 12 mo, clinical data and echocar...


Bone Densitometry Versus Bone Histomorphometry in Renal Transplanted Patients: ...

Ferreira, AC; Mendes, M; Silva, C; Cotovio, P; Aires, I; Navarro, D; Caeiro, F; Salvador, R; Correia, B; Cabral, G; Nolasco, F; Ferreira, A

Bone loss leads to increase risk of fractures in renal transplantation. The aim of this study was to analyse the relationship between bone densitometry (DXA) findings, bone histomorphometry and bone-related molecules 1-year after renal transplantation. We performed a cross-sectional study of de novo renal transplanted patients that agreed to perform a bone biopsy and a DXA examination 1 year after transplantati...


The Role of Bone Volume, FGF23 and Sclerostin in Calcifications and Mortality; ...

Ferreira, AC; Cotovio, P; Aires, I; Mendes, M; Navarro, D; Silva, C; Caeiro, F; Salvador, R; Correia, B; Cabral, G; Nolasco, F; Ferreira, A

Chronic kidney disease-mineral and bone disorder has been associated with increasing morbid-mortality. The aim of this study was to determine the prevalence and phenotype of bone disease before transplantation and to correlate FGF23 and sclerostin levels with bone histomorphometry, and study possible associations between FGF23, sclerostin, and bone histomorphometry with cardiovascular disease and mortality. We ...


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