3 documents found, page 1 of 1
Correction for: Identification of colorectal cancer associated biomarkers: an i...
Fonseca, André; Ramalhete, Sara Ventura; Mestre, André; Neves, Ricardo Pires das; Marreiros, Ana; Castelo Branco, Pedro; Roberto, Vânia Palma
Identification of colorectal cancer associated biomarkers: an integrated analys...
Fonseca, André; Ramalhete, Sara Ventura; Mestre, André; Neves, Ricardo Pires das; Marreiros, Ana; Castelo Branco, Pedro; Roberto, Vânia PalmaColorectal cancer is one of the leading causes of cancer-related deaths worldwide. This complex disease still holds severe problems concerning diagnosis due to the high invasiveness nature of colonoscopy and the low accuracy of the alternative diagnostic methods. Additionally, patient heterogeneity even within the same stage is not properly reflected in the current stratification system. This scenario highlight...
DNA methylation of PI3K/AKT pathway-related genes predicts outcome in patients ...
Faleiro, Inês; Roberto, Vânia Palma; Demirkol Canli, Secil; Fraunhoffer, Nicolas A.; Iovanna, Juan; Gure, Ali Osmay; Link, WolfgangPancreatic cancer (PCA) is one of the most lethal malignancies worldwide with a 5-year survival rate of 9%. Despite the advances in the field, the need for an earlier detection and effective therapies is paramount. PCA high heterogeneity suggests that epigenetic alterations play a key role in tumour development. However, only few epigenetic biomarkers or therapeutic targets have been identified so far. Here we ...