2 documents found, page 1 of 1
Imipramine reverses depressive-like parameters in pneumococcal meningitis survi...
Vilela, Márcia Carvalho; Barichello, Tatiana; Milioli, Graziele; Generoso, Jaqueline S.; Cipriano, Andreza L.; Costa, Caroline S.; Moreira, Ana PaulaPneumococcal meningitis is a severe infectious disease of the central nervous system, associated with acute inflammation and might cause damage to the host, such as deafness, blindness, seizure, and learning deficits. However, infectious diseases can play a significant role in the etiology of neuropsychiatric disturbances. In this context, we evaluated depressive-like parameters; corticosterone and ACTH levels ...
Oxidative stress, cytokine/chemokine and disruption of blood–Brain barrier in n...
Teixeira, Antonio Lucio; Barichello, Tatiana; Lemos, Joelson C.; Generoso, Jaqueline S.; Cipriano, Andreza L.; Milioli, Graziele L.We verify the levels of cytokine/chemokine, myeloperoxidase activity, oxidative stress and disruption of BBB in hippocampus and cortex of the neonate Wistar rats after meningitis by S. agalactiae. In the hippocampus the levels were increased of CINC-1 at 6 h and 12 h, IL-1β at 6, 12 and 24 h, IL-6 at 6, 24 and 96 h, IL-10 at 24, 48 and 96 h and TNF-α at 24 h and 96 h. In the cortex the CINC-1 and IL-1β levels w...