Background: The circadian system regulates several physiological processes, including energy metabolism, through the expression of core clock genes. Animal studies suggest that dietary composition can influence circadian gene expression; however, evidence in humans remains limited. Objective: This study aimed to explore the association between dietary macronutrient intake and the expression of circadian clock g...
Background: The circadian system regulates several physiological processes, including energy metabolism, through the expression of core clock genes. Animal studies suggest that dietary composition can influence circadian gene expression; however, evidence in humans remains limited. Objective: This study aimed to explore the association between dietary macronutrient intake and the expression of circadian clock g...
Effective communication is one of the pillars of the doctor-patient relationship. Hyponatremia is defined as a decrease in serum sodium levels below 135 mEq/L. Objective To draw attention to the possible results of ineffective medical communication and the importance of active listening to the patient. Material and methods Descriptive study of the Case Report type, based on the Case REport guidelines. Case desc...
INTRODUCTION: Eating disorders (ED) are a group of diseases with high morbidity and a significant impact on the lives of children and adolescents. These are biopsychosocial entities, involving individual, family and sociocultural factors. It is known that ED are highly comorbid with other psychiatric disorders. Organic complications are common. Our objective was to characterization of hospitalized patients in t...
The fibroblast growth factor (FGF) family regulates various and important aspects of nervous system development, ranging from the well-established roles in neuronal patterning to more recent and exciting functions in axonal growth and synaptogenesis. In addition, FGFs play a critical role in axonal regeneration, particularly after spinal cord injury, confirming their versatile nature in the nervous system. Due ...
ABSTRACT: The discovery of itaconic acid as a product of citric acid pyrolytic distillation in 1837 opened the possibility of using it as a polymer building block. Itaconic acid, featuring two carboxylic acids and an unsaturated group, can potentially be used as a building block in several chemical syntheses, with a particular emphasis on polymer manufacture. The elucidation of biochemical pathways originating ...
Congenital disorders of glycosylation are a highly variable, rapidly expanding family of genetic diseases that result from defects in the synthesis of glycans. The vast majority of these monogenic diseases are inherited in an autosomal recessive way, but some types follow an autosomal dominant or X-linked inheritance. The present work aimed to review the state of the art of congenital disorders of glycosylation...
Congenital disorders of glycosylation are a highly variable, rapidly expanding family of genetic diseases that result from defects in the synthesis of glycans. The vast majority of these monogenic diseases are inherited in an autosomal recessive way, but some types follow an autosomal dominant or X-linked inheritance. The present work aimed to review the state of the art of congenital disorders of glycosylation...
Melanoma is the most aggressive skin cancer characterized by a high metastatic potential and poor survival rate, leading to major morbidity/mortality. Overweight, obesity and diet composition have been identified as risk factors for many types of cancers. However, there are cancers where obesity is associated with favorable outcomes and this has been coined the “obesity paradox”. Preliminary data obtained by ou...
O presente estudo adotou uma metodologia de investigação quantitativa, com o objetivo de verificar se os estudantes aplicaram e incluíram as ferramentas e instruções das formadoras na concretização do projeto final. Quantificou-se o número de vezes que o grupo de estudantes recorreu às ferramentas digitais exploradas no workshop, e quantos aplicaram na prática as instruções fornecidas pelas formadoras. Os resul...