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Characterization of Antidepressant Consumption in a Portuguese Inland Population.

Soares, Sofia; Rosado, Tiago; Santos, Vítor Hugo; Rei, Cristina; Amantegui, Patricia; Pissarra da Costa, António; Chaves, Telma; Valente, Rita

Mental disorders are a growing global concern, with depression being among the most prevalent. Portugal ranks second in antidepressant consumption within the OECD, following a threefold increase between 2000 and 2020. In inland regions such as Beira Interior, reduced healthcare services and distance from major hospitals further complicate access to care. This study analysed 142 patients from Beira Interior unde...


Chromatographic determination of antidepressants in plasma and saliva: Towards ...

Soares, Sofia; Rosendo, Luana; Fonseca, Suzana; Gonçalves, Nuno; Franco, João; da Costa, António Pissarra; Rosado, Tiago; Barroso, Mário

Drug monitoring of antidepressants in plasma and oral fluid represents a valuable tool in clinical practice, enabling the optimisation of treatment efficacy and the reduction of adverse effects. Given the significant interindividual variability in antidepressant response-driven by factors such as metabolism, drug-drug interactions, and adherence to therapy-drug monitoring facilitates dose adjustment based on me...


Dyadic vs. triadic taxonomy of body representation: A scoping review of brain m...

Santos, Hugo; Baleia, Isabel; Brandão, Rita; Santos, Gonçalo; Marques, Inês; Lamarão, João; Morais, José; Correia, Leonor; Martins, Maria Elisabete

Introduction: Body representation refers to how the brain processes information about the body, traditionally categorised by the dyadic taxonomy into body schema and body image. However, the triadic taxonomy proposes the inclusion of the body structural description and body semantics. Objectives: This scoping review retrospectively mapped existing neuroimaging studies to the dimensions proposed by dyadic taxono...


The role of TMPRSS6 gene variants in different types of iron deficiency anaemia...

Gonçalves, Lúcia; Nobre Jesus, Gustavo; Afonso, Celina; Vieira, Albertina; Maia, Raquel; Correia, Leonor; Faustino, Paula

Objective: Iron-refractory iron-deficiency anaemia (IRIDA) is a rare autosomal-recessive disease characterized by severe hypochromic microcytic anemia, low serum iron and transferrin saturation, normal-high ferritin and inappropriate high levels of the hormone hepcidin. Patients are unresponsive to iron oral treatment and present a slow persistent response to intravenous iron injections. The disease is caused b...


A gestão por processos e a aposta nas pessoas no Serviço de Aquisições e Tratam...

Barreto, Adalberto; Santos, Conceição; Guimarães, Edite; Paiva, José; Correia, Leonor; Pinto, Leonor Gaspar

No contexto presente em que é grande o interesse e a pressão política para que o desempenho da Administração Pública (central e local) seja avaliado, o tema da gestão da qualidade, não só mantêm a sua actualidade, como continua a prefigurar-se como uma estratégia eficaz para fazer fase aos desafios de rigor nas despesas e de valorização social dos serviços públicos, designadamente das bibliotecas. No âmbito das...


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