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A proof-of-concept study aiming for the integration of an optical biosensor in ...

Correia, Margarida O.; Sousa, Paulo Jorge Teixeira; Rodrigues, Raquel Oliveira; Minas, Graça

Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is marked by the abnormal production of amyloid-beta (Aβ) fibrils, a key biomarker for diagnosis and illness monitoring. Advanced microfluidic devices, such as brain-on-a-chip (BoC), are innovative preclinical tools with the potential to revolutionize AD early diagnosis and treatment. However, existing BoCs face limitations, including challenge...

Date: 2025   |   Origin: RepositóriUM - Universidade do Minho
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