8 documents found, page 1 of 1
Xyloglucan and Concanavalin A based dressings in the topical treatment of mice ...
Arruda, Isabel R. S.; Souza, Marthyna P.; Soares, Paulo A. G.; Albuquerque, Priscilla B. S.; Silva, Túlio D.; Medeiros, Paloma L.; Silva, Marcia V.For medical biomaterials, xyloglucan dispersions can form films or gels to be applied as a wound dressing. For this purpose, the structural characterization of xyloglucan dressing (XG) and xyloglucan dressing containing 0.5 mg/mL of concanavalin A (XGL) was performed. The lectin release capacity and stability, cytotoxicity, and pro-wound healing effects were also investigated. XG and XGL films were prepared by ...
Fatty acid-rich volatile oil from Syagrus coronata seeds has larvicidal and ovi...
Marriel, Nadja B.; Santos, Leilane M. M.; Nascimento, Jéssica S.; Santos, Mirela A. G.; Bezerra-Silva, Patrícia C.; Rocha, Suyana K. L.This work evaluated the potential of a volatile oil extracted from Syagrus coronata seeds for the control of Aedes aegypti. The oil was extracted by hydrodistillation, characterized by gas chromatography-mass spectrometry (GC-MS), and evaluated for larvicidal and ovicidal activities, as well as for influence on the choice of oviposition site by females. The effects of the oil on swimming activity of larvae were...
Healing activity evaluation of the galactomannan film obtained from Cassia gran...
Albuquerque, Priscilla B. S.; Soares, Paulo A. G.; Aragão-Neto, Adelmo C.; Albuquerque, Giwellington S.; Silva, Luís C. N.; Lima-Ribeiro, Maria H. M.Galactomannan films from Cassia grandis seeds, associated or not with Cramoll 1,4, were used on topical wounds of rats for the evaluation of the healing process during 14 days. All of the films were evaluated by cytotoxic assay, FTIR and lectin hemagglutinating activity (HA). Forty-five male rats were submitted to aseptic dermal wounds (Ø = 0.8 cm) and divided in groups (n = 15): control, test 1, and test 2, tr...
Investigating a galactomannan gel obtained from Cassia grandis seeds as immobil...
Albuquerque, Priscilla B. S.; Silva, Caroline S.; Soares, Paulo A. G.; Barros Junior, Wilson; Correia, Maria T. S.; Coelho, Luana C. B. B.Characterization, with emphasis on the rheological properties, of Cassia grandis seeds galactomannan gel containing immobilized Cramoll 1,4 is presented. The gels, with and without immobilized Cramoll 1,4, were evaluated along time by rheometry, pH, color, microbial contamination and lectin hemagglutinating activity (HA). Rheological determinations confirmed the gels to be very stable up to 30 days with variati...
Structure and rheological properties of a xyloglucan extracted from Hymenaea co...
Arruda, Isabel R. S.; Albuquerque, Priscilla B. S.; Santos, Gustavo R. C.; Silva, Alexandre G.; Mourão, Paulo A. S.; Correia, Maria T. S.Hymenaea courbaril var courbaril seed xyloglucan was efficiently extracted with 0.1 M NaCl, followed by ethanol precipitation (yield = 72 ± 5% w/w). Its amorphous structure was identified by the pattern of X-ray diffraction. The monosaccharide composition was determined by GC/MS analysis of the alditol acetates and showed the occurrence of glucose:xylose:galactose:arabinose (40:34:20:6). One-(1D) and two-dimens...
Characterization and rheological study of the galactomannan extracted from seed...
Albuquerque, Priscilla B. S.; Barros Junior, Wilson; Santos, Gustavo R. C.; Correia, Maria T. S.; Mourão, Paulo A. S.; Teixeira, J. A.Galactomannan extracted from seeds of Cassia grandis with 0.1 M NaCl, followed by ethanol precipitation, presented a yield of 36 ± 8%. The polysaccharide has a constant mannose/galactose ratio (2.44:1). Methylation analysis, one and two dimensional NMR spectroscopy confirmed that the polysaccharide has a central core composed of 4-linked β-mannose units, with branches of galactose, linked to the carbohydrate co...
Development and characterization of hydrogels based on natural polysaccharides ...
Soares, Paulo A. G.; Bourbon, A. I.; Vicente, A. A.; Andrade, Cesar A. S.; Barros Junior, Wilson; Correia, Maria T. S.; Pessoa Júnior, AdalbertoThe development of hydrogels based on natural polysaccharides was investigated by preparing mixtures of policaju/chitosan at weight ratios of 1:4 and 2:3. Utilizing dynamic light scattering (DLS) techniques for these mixtures, an increase on the hydrodynamic particle radius was observed varying their pH from 3.0 to 12.0. Furthermore, a reduction of ζ-potential was also observed for the same pH interval. Followi...
Strategies to obtain lectins from distinct sources
Santos, Andréa F. S.; Napoleão, Thiago H.; Bezerra, Rosiely F.; Carvalho, Elba V. M. M.; Correia, Maria T. S.; Paiva, Patrícia M. G.Lectins are proteins or glycoproteins that bind specifically to mono, oligo or polysaccharides. They are important biotechnological tools and have been isolated from microorganisms, higher fungus, lichens, plants and animals. Different purification strategies are used to obtain pure lectins. It is important to approach the principles of each method to be used in protein purification before start to work in this...