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Diagnosis of monoclonal gammopathy of renal significance

Correia,Sofia O; Santos,Sofia; Martins,La Salete; Santos,Josefina

Monoclonal gammopathies are a heterogeneous group of disorders characterized by clonal proliferation of immunoglobulin produced by B-lymphocytes or plasma cell clone. The term monoclonal gammopathy of renal significance (MGRS) was introduced to distinguish monoclonal gammopathies that result in the development of kidney disease from those that are benign. Screening for monoclonal immunoglobulin and an appropria...

Date: 2018   |   Origin: SciELO Portugal

Acute tubulointersticial nephritis with uveitis: A report of two cases

Silva,Filipa; Correia,Sofia O; Castro,Ana; Moreira,Carla; Santos,Sofia; Malheiro,Jorge; Santos,Josefina; Martins,La Salete; Cabrita,António

Tubulointersticial nephritis and uveitis syndrome is an idiopathic and rare cause of acute kidney injury that should not overlooked, because it usually requires specific therapeutic interventions. We report two distinct cases: a young and an elder female. Both cases presented with unspecific constitutional symptoms but had different onset of renal and ocular involvement. Both were treated with topical and syste...

Date: 2018   |   Origin: SciELO Portugal

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