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Excess perigestational folic acid exposure induces metabolic dysfunction in pos...
Keating, E; Correia-Branco, A; Araújo, JR; Meireles, M; Fernandes, R; Guardão, L; Guimarães, JT; Martel, F; Calhau, CThe aim of this study was to understand whether high folic acid (HFA) exposure during the perigestational period induces metabolic dysfunction in the offspring, later in life. To do this, female Sprague-Dawley rats (G0) were administered a dose of folic acid (FA) recommended for pregnancy (control, C, 2 mg FA/kg of diet, n=5) or a high dose of FA (HFA, 40 mg FA/kg of diet, n=5). Supplementation began at mating ...
Date: 2015
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Origin: Repositório Aberto da Universidade do Porto