108 documents found, page 1 of 11
Diaphragmatic hernia repair porcine model to compare the performance of biodegr...
Scuglia, Marianna; Frazão, Laura P.; Miranda, Alice Augusta Macedo; Martins, Albino; Barbosa-Sequeira, Joana; Coimbra, Diana; Longatto, AdhemarBackground Patch repair of congenital diaphragmatic hernia (CDH) using Gore-Tex® is associated with infection, adhesions, hernia recurrence, long-term musculoskeletal sequels and poor tissue regeneration. To overcome these limitations, the performance of two novel biodegradable membranes was tested to repair CDH in a growing pig model. Methods Twelve male pigs were randomly assigned to 3 diferent groups of 4 an...
Medicina: ciência, educação e inovação ao “serviço da vida humana”
Correia-Pinto, Jorge; Leite-Almeida, Hugo; Palha, Joana Almeida; Ludovico, Paula; Morgado, Pedro; Leão, Cecília[Excerto] Escola, desde sempre, se apresentou como um espaço de liberdade e diversidade que fomenta a curiosidade e a produção de conhecimento, conferindo autonomia científica, técnica e profissional a todos os que nela se formam e diferenciam. Esta Escola representa, a todos os níveis, um marco inovador na formação médica, primando pela excelência, não só nos eixos de atividade tradicionais – pedagógico, cient...
Comparative study of e-cigarette aerosol and cigarette smoke effect on ex vivo ...
Silva-Ribeiro, Tiago; Coelho, Eduardo João Louro; Genisheva, Zlatina; Oliveira, José Maria; Correia-Pinto, Jorge; Sampaio, Paula; Moura, Rute S.Electronic cigarette usage has significantly expanded among young people and pregnant women in the last decade. Although there are already some data regarding the short- and long-term consequences of e-cigarettes on human health, their effect on embryo and lung development still needs to be fully disclosed. In this sense, this study describes, for the first time, the impact of electronic cigarette aerosol on ea...
Study of the compression behavior of functionally graded lattice for customized...
Veloso, Fernando; Miranda, Daniel; Morais, Pedro; Torres, Helena; Oliveira, Bruno; Correia-Pinto, Jorge; Pinho, AntónioDeformational plagiocephaly is a head deformity that occurs in newborns, treated in severe cases with helmets named cranial remodeling orthoses (CRO). Current CROs can fail to adapt to head growth, causing excessive pressure sores and other complications, and may lead to poor clinical results. In this work, we experimentally and numerically study the compressive behavior of a functionally graded lattice that ma...
Automatic assessment of Pectus Excavatum severity from CT images using deep lea...
Silva, Bruno André Pires; Pessanha, Inês; Correia-Pinto, Jorge; Fonseca, Jaime C.; Queirós, Sandro Filipe MonteiroPectus excavatum (PE) is the most common abnormality of the thoracic cage, whose severity is evaluated by extracting three indices (Haller, correction and asymmetry) from computed tomography (CT) images. To date, this analysis is performed manually, which is tedious and prone to variability. In this paper, a fully automatic framework for PE severity quantification from CT images is proposed, comprising three st...
Thoracoscopic Lobectomy for Congenital Pulmonary Airway Malformation with Prena...
Barroso, Catarina; Felizes, Andreia; Silva, Ana Raquel; Braga, Inês; Gonçalves, Marta; Salgado, Helena; Gonçalves, Augusta; Cadilhe, AlexandraINTRODUCTION: Congenital pulmonary airway malformations (CPAM) are increasingly diagnosed in the prenatal period raising concerns on the post-natal management of asymptomatic cases. Favoring early resection are the concepts of better compensatory lung growth, and prevention of long-term risk of infection and malignancy. Our aim was to review the results of our conduct over the years, in which we promote early t...
Developmental pathways underlying lung development and congenital lung disorders
Caldeira, Inês; Silva, Hugo Miguel Fernandes; Costa, Daniela Machado; Correia-Pinto, Jorge; Moura, Rute S.Lung organogenesis is a highly coordinated process governed by a network of conserved signaling pathways that ultimately control patterning, growth, and differentiation. This rigorously regulated developmental process culminates with the formation of a fully functional organ. Conversely, failure to correctly regulate this intricate series of events results in severe abnormalities that may compromise postnatal s...
Synthetic infant head shapes with deformational plagiocephaly: concept and 3D m...
Veloso, Fernando; Torres, Helena R.; Gomes-Fonseca, João; Oliveira, Bruno; Ruediger, Mario; Hahn, Gabriele; Pinho, António C. M.; Correia-Pinto, JorgeDeformational plagiocephaly (DP) is an asymmetric flattening of the occiput, which can be caused by a preference for a sleeping position or a restriction of the head rotation. The absence of a standardized method to quantify the severity of DP is problematic, being the severity of the condition the main factor for the recommendation of a specific treatment. To improve the quality of assessment of DP and thanks ...
Measurements in first-trimester abortion products a pathologic study
Cardoso, Rosete Maria Amorim Novais Nogueira; Sousa, Sara; Braga, A. C.; Azevedo, Ana; Pereira, Nuno; Carmo, Olímpia; Tavares, Maria PurificaçãoContext.-Related to the advances in prenatal diagnosis and the emergence of medically challenging situations, there has been an increased interest in conducting a pathologic study of first-trimester abortion products. Objective.-To evaluate measurements across a large group of first-trimester spontaneous abortion specimens. Potential goals include a validation of prenatal embryo and gestational-sac measurements...
Technical note: assessment of electromagnetic tracking systems in a surgical en...
Fonseca, João Luís Gomes; Veloso, Fernando; Queirós, Sandro Filipe Monteiro; Morais, Pedro André Gonçalves; Pinho, António C. M.; Fonseca, Jaime C.Purpose Electromagnetic tracking systems (EMTSs) have been proposed to assist the percutaneous renal access (PRA) during minimally invasive interventions to the renal system. However, the influence of other surgical instruments widely used during PRA (like ureteroscopy and ultrasound equipment) in the EMTS performance is not completely known. This work performs this assessment for two EMTSs [Aurora (R) Planar F...