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Finely tuned fiber-based porous structures for bone tissue engineering applicat...

Ribeiro, Viviana; Silva-Correia, Joana; Morais, Alain; Correlo, Vitor M.; Marques, Alexandra P.; Ribeiro, Ana; Silva, Carla; Durães, Nelson


Textile-based silk scaffolds for bone tissue engineering applications

Ribeiro, Viviana; Morais, Alain; Correlo, Vitor M.; Marques, Alexandra P.; Ribeiro, Ana; Silva, Carla; Durães, Nuno; Bonifácio, Graça; Sousa, Rui

INTRODUCTION: Scaffolds developed for bone tissue engineering (TE) need to facilitate and promote cell adhesion, proliferation and neo-tissue formation. They must possess specific properties to allow the new tissue to integrate with the material, without inducing any inflammatory response. The intra-architectural scaffold geometry, porosity, scaffold material and surface area play important roles in this proces...


Development and characterization of PHB-HV based 3D scaffolds for a tissue engi...

Samy, S. M.; Silva, Nuno A.; Correlo, Vitor M.; Fraga, Joana S.; Pinto, Luísa; Teixeira-Castro, Andreia; Leite-Almeida, Hugo; Almeida, Armando

Spinal cord injury (SCI) leads to devastating neurological deficits. Several tissue engineering (TE)- based approaches have been investigated for repairing this condition. Poly (3-hydroxybutyrateco- 3-hydroxyvalerate) (PHB-HV) is found to be particularly attractive for TE applications due to its properties, such as biodegradability, biocompatibility, thermoplasticity and piezoelectricity. Hence, this report add...


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