4 documents found, page 1 of 1
Teste Serológico: Um Auxílio no Diagnóstico de COVID-19
Fernandes,Catarina Borges; Sampaio,António Marcos; Ramalho,Paulo Torres; Veiga,Rui; Leite,Alberto; Alvelos,Margarida Pereira e; Bettencourt,PauloResumo O surgimento do vírus da síndrome respiratória aguda grave - coronavírus 2, responsável pela doença COVID-19, conduziu a um rápido desenvolvimento de métodos moleculares e serológicos para o seu diagnóstico. Apesar de o teste molecular de amostras do trato respiratório ser o teste de diagnóstico standard, verifica-se um interesse crescente pelo uso de exames serológicos, mas existe, ainda, evidência limi...
Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensate...
Ferreira,João Pedro; Santos,Mário; Oliveira,José Carlos; Marques,Irene; Bettencourt,Paulo; Carvalho,HenriqueBackground: Matrix metalloproteinases (MMPs) are a family of enzymes important for the resorption of extracellular matrices, control of vascular remodeling and repair. Increased activity of MMP2 has been demonstrated in heart failure, and in acutely decompensated heart failure (ADHF) a decrease in circulating MMPs has been demonstrated along with successful treatment. Objective: Our aim was to test the influenc...
Cardiomiopatia Tóxica Dilatada: Reconhecendo uma Doença Potencialmente Reversível
Rangel,Inês; Amorim,Marta; Gonçalves,Alexandra; Sousa,Carla; Bettencourt,Paulo; Maciel,Maria Júlia
Clinical Epidemiology of Chronic Obstructive Pulmonary Disease
Mascarenhas,Joana; Bettencourt,Paulo; Azevedo,AnaChronic obstructive pulmonary disease (COPD) is responsible for early morbidity and high mortality and significant costs to health systems. Smoking remains the main risk factor for COPD but additional factors, such as indoor and outdoor air pollution, occupational exposure and genetic susceptibility are increasingly recognized. The burden of COPD has been difficult to estimate owing to the multiple definitions ...