Due to the high prevalence of cannabinoids in forensic toxicology analysis, it is crucial to have an efficient method that allows the use of a small sample amount and that requires a minimal sample preparation for the determination and quantification of low concentrations. A simple, highly selective and high throughput liquid chromatography–tandem mass spectrometry methodology (LC–MS-MS-MS3) was developed for t...
Portugal recebeu um grande influxo de imigrantes oriundos de diversos países. Dentro destes destacam-se aqueles vindos de países pertencentes à Comunidade dos Países de Língua Portuguesa (CPLP). Em 2022 contabilizaram-se cerca de 350 000 imigrantes oriundos destes países, aproximadamente 45% do número total de imigrantes a residir em Portugal. A introdução destas populações imigrantes acrescenta variabilidade g...
SARS-CoV-2 is a recent coronavirus that appeared in the end of 2019. The World Health Organization named the infection, caused by this new coronavirus, Coronavirus Disease 2019 (COVID-19). This disease was considered a pandemic on March 11th 2020 by the same organization. Coronaviruses rapidly acquire new mutations and, consequently, new variants keep emerging. There are some variants with an associated risk in...
Migration is one of the main factors for genetic variability within populations. Currently, the Portuguese population, and particularly the population from Lisboa, welcomes a considerable number of immigrants. Brazilian immigrants are the main foreign community in Portugal, with about 184 000 individuals in 2020. Mithocondrial DNA (mtDNA), due to its unique characteristics such as being exclusively maternal inh...
The population in this study is composed of individuals who were born and live in Lisbon, and whose parents were also born in Lisbon. Due to the lacking of population studies regarding the following new STRs (Short Tandem Repeats): D2S1360, D3S1744, D4S2366, D5S2500, D6S474, D7S1517, D8S1132, D10S2325, D12S391, D21S2055, it was necessary to evaluate their frequencies in Lisbon’s population. Often, in complex ca...
At the scope of criminal and forensic investigations, the criminal authorities, health professionals, and many other intervenients can obtain different kinds of samples with biological material. The study of those samples by DNA laboratories can lead to the achievement of genetic profiles. CODIS and similar informatic DNA databases, by storing and managing those genetic profiles, can aid at criminal investigati...
Typing X-chromosome markers (ChrX) is important to complement the analysis of Y and autosomal (AS) short tandem repeats (STR). The main field of the ChrX is kinship investigations, especially investigations of mother/son, father/daughter and complex kinship tests. When the alleged father is not present, the ChrX investigation is more accurate because the mean exclusion chance of X-STRs in these cases is higher....
Child custody decisions are among the most difficult is one of the most difficult for judges to make. The possibility of child abuse allegations or parents’ deviant/psychopathologic behaviours within this context, make the decision further complicated. Based on jurisprudence the listening of children opinion is a way to protect their best interest. In fact children have the right to express an opinion in all ma...