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Umbilical-Cord-Derived Mesenchymal Stromal Cells Modulate 26 Out of 41 T Cell S...

Laranjeira, Paula; Dos Santos, Francisco; Salvador, Maria João; Simões, Irina N.; Cardoso, Carla M. P.; Silva, Bárbara M.; Henriques-Antunes, Helena

Systemic sclerosis (SSc) is an immune-mediated disease wherein T cells are particularly implicated, presenting a poor prognosis and limited therapeutic options. Thus, mesenchymal-stem/stromal-cell (MSC)-based therapies can be of great benefit to SSc patients given their immunomodulatory, anti-fibrotic, and pro-angiogenic potential, which is associated with low toxicity. In this study, peripheral blood mononucle...


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