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Saliva Molecular Testing Bypassing RNA Extraction is Suitable for Monitoring an...

Alenquer, M; Milheiro Silva, T; Akpogheneta, O; Ferreira, F; Vale-Costa, S; Medina-Lopes, M; Batista, F; Garcia, AM; Barreto, VM; Paulino, C; Costa, J

Background: Adults are being vaccinated against SARS-CoV-2 worldwide, but the longitudinal protection of these vaccines is uncertain, given the ongoing appearance of SARS-CoV-2 variants. Children remain largely unvaccinated and are susceptible to infection, with studies reporting that they actively transmit the virus even when asymptomatic, thus affecting the community. Methods: We investigated if saliva is an ...


Distinguishing Kingella kingae from Pyogenic Acute Septic Arthritis in Young Po...

Gouveia, C; Subtil, A; Norte, S; Arcangelo, J; Santos, MA; Corte-Real, R; Simões, MJ; Canhão, H; Tavares, D

Background: We aim to identify clinical and laboratorial parameters to distinguish Kingella kingae from pyogenic septic arthritis (SA). (2) Methods: A longitudinal, observational, single-centre study of children < 5 years old with microbiological positive SA admitted to a paediatric hospital from 2013-2020 was performed. Clinical and laboratorial data at admission and at 48 h, as well as on treatment and evolut...


Implementing an Influenza Vaccine Effectiveness Study in a Hospital Context in ...

Machado, A; Gomez, V; Panarra, A; Poças, J; Corte-Real, R; Peres, MJ; Nunes, B

Introduction: The project ‘Integrated Monitoring of Vaccines in Europe’ aimed to measure seasonal influenza vaccine effectiveness against hospitalised adults, aged 65 years and over, with influenza. We describe the protocol implementation in Portugal. Material and Methods: We implemented a test-negative design, targeting community-dwelling patients aged 65 years old and over hospitalised with severe acute respi...


Legionella: Novas Abordagens, Novas Necessidades

Costa Santiago, R; Ramos, S; Corte-Real, R; Manzano, MJ; Infante, J

INTRODUÇÃO: O CHLC desenvolve, desde há vários anos, procedimentos contra o crescimento e proliferação da Legionella, monitorizando e auditando as estruturas e as práticas. De acordo com as recentes orientações e normas emanadas pela DGS, surge a necessidade de criar novos instrumentos para a avaliação do risco e dar resposta às necessidades do Centro Hospitalar. OBJETIVO Identificar os fatores de risco que det...


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