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Alzheimer’s detection through structural MRI texture analysis

Oliveira, M. J.; Ribeiro, P.; Rodrigues, P. M.

Introduction: Alzheimer’s Disease (AD) is the most common cause of dementia. It affects mostly the elderly and is directly impacted by the observed growth of life expectancy. AD manifests as a chronic and progressive neurodegenerative disease, gradually deteriorating memory and cognitive abilities, and diminishing day-to-day quality of life. As the global population ages, understanding and addressing the challe...


Assessment of the post-acute covid-19 syndrome cardiovascular effect through EC...

Ribeiro, P.; Souza, C. C. C. D.; Camerino, C. M. C.; Pordeus, D.; Leite, C. F.; Marques, J. A. L.; Madeiro, J. P.; Rodrigues, P. M.

Introduction: SARS-CoV-2, a virus responsible for the emergence of the life-threatening disease known as COVID-19, exhibits a diverse range of clinical manifestations. The spectrum of symptoms varies widely, encompassing mild to severe presentations, while a considerable portion of the population remains asymptomatic. COVID-19, primarily a respiratory virus, has been linked to cardiovascular complications in so...


Speech non-linear multiband-time-series analysis for detecting Alzheimer’s disease

Silva, M. G.; Ribeiro, P.; Bispo, B. C.; Rodrigues, P. M.

Introduction: Alzheimer’s Disease (AD) is a prevalent neurodegenerative disorder, anticipated to triple in cases by 2050. It constitutes 50-75% of dementia cases and currently lacks a cure. Early diagnosis is crucial, allowing for treatments that may delay its progression. Traditional diagnostic methods, though effective, are invasive and expensive. Speech signal analysis has emerged as a promising non-invasive...


gBIOT - Nutraceutical biopolymeric-biocatalytic microbot against gut inflammato...

Sousa, A. S.; Pintado, M. M.; Matos, R. D.; Sousa, C. C.; Machado, M. F.; Coelho, M.; Rodrigues, P. M.; Magalhães, A. M.; Coscueta, E. R.

gBiOT is a novel project that proposes micro-robotic technology for nutraceuticals and therapeutic foods for gastrointestinal tract disorders. Gastrointestinal disorders have high prevalence and morbidity, leading to neoplasia and cancer. Recent advances in nanotechnology have opened up new opportunities in the food sector, allowing for the development of health-food products containing nanosized ingredients th...


A systematic review of natural products for skin applications: targeting inflam...

Fernandes, A.; Rodrigues, P. M.; Pintado, M.; Tavaria, F. K.

Background: Every day the skin is constantly exposed to several harmful factors that induce oxidative stress. When the cells are incapable to maintain the balance between antioxidant defenses and reactive oxygen species, the skin no longer can keep its integrity and homeostasis. Chronic inflammation, premature skin aging, tissue damage, and immunosuppression are possible consequences induced by sustained exposu...


β-glucans derived from mushroom Coriolus versicolor for applications on skin wo...

Fernandes, A. S.; Rodrigues, P. M.; Pintado, M.; Tavaria, F. K.

The beneficial effects of natural compounds in cosmeceutical and biopharmaceutic fields have been extensively studied over the years, and gained popularity because of their distinct advantages, including fewer side effects, better tolerance, and relatively low expenses. Currently, with the growing demand for the use of nature-derived molecules, the research aiming for new biomolecules has increased. Beta-glucan...



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