6 documents found, page 1 of 1
Adrenal Vein Sampling in the Management of Primary Aldosteronism: The Added Val...
Manique, I; Amaral, S; Matias, A; Bouça, B; Serranito, S; Torres, J; Gutu, O; Bilhim, T; Coimbra, E; Rodrigues, I; Godinho, C; Cortez, L; Silva-Nunes, JIntroduction: Primary aldosteronism is the most common cause of secondary hypertension. Adrenal vein sampling is the gold standard for subtyping primary aldosteronism. However, this procedure is technically challenging and often has a low success rate. Our center is one of the very few performing this technique in our country with an increasing experience. Objective: The aim of this study was to evaluate the ro...
A Common Variant in the CDK8 Gene Is Associated with Sporadic Pituitary Adenoma...
Gaspar, L; Gonçalves, C; Fonseca, F; Carvalho, D; Cortez, L; Palha, A; Barros, I; Nobre, E; Duarte, J; Amaral, C; Bugalho, MJ; Marques, O; Pereira, BThe majority of pituitary adenomas occur in a sporadic context, and in the absence of known genetic predisposition. Three common variants at the NEBL (rs2359536), PCDH15 (rs10763170) and CDK8 (rs17083838) loci were previously associated with sporadic pituitary adenomas in the Han Chinese population, but these findings have not yet been replicated in any other population. The aim of this case-control study was t...
Leydig Cell Tumour and Mature Ovarian Teratoma: Rare Androgen-Secreting Ovarian...
Palha, A; Cortez, L; Tavares, AP; Agapito, AAndrogen-secreting ovarian tumours are extremely rare accounting for <5% of all ovarian neoplasms. They are more frequent in postmenopausal women and should be suspected in the case of a rapid onset of androgenic symptoms. We report 4 cases of postmenopausal women who presented with signs of virilisation. All patients revealed increased serum levels of testosterone, normal dehydroepiandrosterone-sulfate and neg...
Diabetes e Gravidez. Experiência da Consulta de Medicina Materno-Fetal do Servi...
Fernades, ME; Leitão, C; Henriques, O; Cortez, L; Campos, OOs autores realizaram um estudo retrospectivo das 87 grávidas vigiadas na Consulta de Diabetes do Hospital de Dona Estefânia com diabetes pré-gestacional tipo 1 e 2 e diabetes gestacional, durante um período de 2 anos. Analisararn a idade das grávidas, raça, paridade, tipo de diabetes, patologia associ ada, antecedentes familiares de diabetes, idade gestacional em que foi feito o diagnóstico de diabetes, insuli...
Myxedema coma.
Fonseca, F; Cortez, L; Guerra, L; Afonso, A; Agapito, A; Malheiro, F; da Costa, CFive patients, 4 female and 1 male, aged 45 to 73, were observed in myxedema coma between 1984 and 1992. In three patients hypothyroidism was not known. Depressed consciousness, hypothermia, bradycardia and no goiter were common to all and a precipitating factor could be identified in 3 of them. Therapy included L-thyroxine and/or triiodothyronine by nasogastric tube, hydrocortisone and supportive measures. Out...
Coma Mixedematoso
Fonseca, F; Cortez, L; Guerra, L; Afonso, A; Agapito, A; Malheiro, F; Charneco da Costa, JOs AA. apresentam 5 casos de coma mixedematoso observados no período de 1984 a 1992. Trata-se de 4 doentes do sexo feminino e 1 do sexo masculino com idades compreendidas entre os 45 e 73 anos. Em 3 doentes não havia diagnóstico prévio de hipotiroidismo. A depressão do estado de consciência, a hipotermia, a bradicardia e a ausência de bócio eram comuns aos 5 doentes. Foi identificado factor desencadeante em 3 d...