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Predictors of drooling severity in people with Parkinson’s disease

Nascimento, David; Meira, Bruna; Garcez, Luís; Abreu, Daisy; Outeiro, Tiago; Guimarães, Isabel; Ferreira, Joaquim J.

Background Drooling, defned as the unintentional loss of saliva from the anterior oral cavity, remains poorly understood in terms of the underlying clinical factors in people with Parkinson’s disease (PwP). This study aims to clarify these factors by analyzing predictors and secondarily the correlates with the severity of drooling in PwP. Methods We conducted a cross-sectional study involving 42 PwP with drooli...


Natural history of familial cerebral cavernous malformation syndrome in childre...

Geraldo, Ana Filipa; Alves, Cesar Augusto P. F.; Luis, Aysha; Tortora, Domenico; Guimarães, Joana; Abreu, Daisy; Reimão, Sofia; Pavanello, Marco

Purpose: There is limited data concerning neuroimaging findings and longitudinal evaluation of familial cerebral cavernous malformations (FCCM) in children. Our aim was to study the natural history of pediatric FCCM, with an emphasis on symptomatic hemorrhagic events and associated clinical and imaging risk factors. Methods: We retrospectively reviewed all children diagnosed with FCCM in four tertiary pediatric...


TREATMENT OF ARTERIAL PATHOLOGY IN THE PORTUGUESE NATIONAL HEALTH SERVICE — A R...

Bastos Goncalves, Frederico; Sousa, Paulo; Abreu, Daisy; Menezes, José Daniel; Mansilha, Armando

Introduction: The analysis of administrative databases, using administrative data from hospital codification, is an important tool to improve knowledge and management of healthcare. Through this, it is possible to evaluate tendencies as well as monitor and evaluate generic outcomes. Method: The present report is a result of a collaboration protocol between the Portuguese Society of Angiology and Vascular Surger...

Date: 2021   |   Origin: Angiologia e Cirurgia Vascular

Kinematic and clinical outcomes to evaluate the efficacy of a multidisciplinary...

Bouça-Machado, Raquel; Branco, Diogo; Fonseca, Gustavo; Fernandes, Raquel; Abreu, Daisy; Guerreiro, Tiago; Ferreira, Joaquim J

Introduction: Functional mobility (FM) is a concept that incorporates the capacity of a person to move independently and safely to accomplish tasks. It has been proposed as a Parkinson's disease (PD) functional and global health outcome. In this study, we aimed to identify which kinematic and clinical outcomes changes better predict FM changes when PD patients are submitted to a specialized multidisciplinary pr...


Cross-cultural adaptation and validation of the swallowing disturbance question...

Cardoso, Rita; Guimarães, Isabel; Santos, Helena; Carvalho, Joana; Abreu, Daisy; Gonçalves, Nilza; Ferreira, Joaquim

Introduction: To date, no valid outcome measure has been developed in European Portuguese (EP) to evaluate the Parkinsons’ Disease (PD) patients’ (PwP) reports regarding their swallowing disturbances. Objectives: The aim of this study was to translate and cross-culturally adapt the Swallowing Disturbance Questionnaire (SDQ) and the Sialorrhea Clinical Scale for PD (SCS-PD) into EP and to determine its clinimetr...


Impact of public health initiatives on acute coronary syndrome fatality rates i...

Abreu, Daisy; Sousa, Paulo; Matias Dias, Carlos; Pinto, Fausto

Introduction and objective: Every year cardiovascular disease (CVD) causes 3.9 million deaths in Europe. Portugal has implemented a set of public health policies to tackle CVD mortality: a smoking ban in 2008, a salt reduction regulation in 2010 and the coronary fast-track system (FTS) for acute coronary syndrome (ACS) in 2007. Our goal in this study was to analyze the impact of these three public health polici...


Levodopa response in later stages of Parkinson's disease: a case-control study

Fabbri, Margherita; Coelho, Miguel; Abreu, Daisy; Ferreira, Joaquim J

Levodopa (l-dopa) remains the gold-standard of Parkinson's disease (PD) treatment. With disease progression, l-dopa efficacy on PD cardinal motor symptoms may decrease. Nevertheless, l-dopa has a safer profile compared to other antiparkinsonian drugs, especially in elderly and frail patients. Indeed, a simplification of drug regimen in later disease stages may be beneficial. We have recently reported a smaller ...


Cross-cultural adaptation and validation of the Swallowing Disturbance Question...

Cardoso, Rita; Guimarães, Isabel; Santos, Helena; Carvalho, Joana; Abreu, Daisy; Gonçalves, Nilza; Ferreira, Joaquim J

Introduction: To date, no valid outcome measure has been developed in European Portuguese (EP) to evaluate the Parkinsons' Disease (PD) patients' (PwP) reports regarding their swallowing disturbances. Objectives: The aim of this study was to translate and cross-culturally adapt the Swallowing Disturbance Questionnaire (SDQ) and the Sialorrhea Clinical Scale for PD (SCS-PD) into EP and to determine its clinimetr...


Impact of public health initiatives on acute coronary syndrome fatality rates i...

Abreu, Daisy; Sousa, Paulo; Matias Dias, Carlos; Pinto, Fausto J.

Introduction and Objective: Every year cardiovascular disease (CVD) causes 3.9 million deaths in Europe. Portugal has implemented a set of public health policies to tackle CVD mortality: a smoking ban in 2008, a salt reduction regulation in 2010 and the coronary fast-track system (FTS) for acute coronary syndrome (ACS) in 2007. Our goal in this study was to analyze the impact of these three public health polici...


Dysphagia predicts poor outcome in late-stage Parkinson's disease

Fabbri, Margherita; Coelho, Miguel; Abreu, Daisy; Guedes, Leonor Correia; Rosa, Mario M.; Godinho, Catarina; Cardoso, Rita; Guimarães, Isabel

"BACKGROUND: Few data exist on the rate of clinical progression for Parkinson's disease (PD) patients who have entered a late stage of the disease. OBJECTIVE: Study the clinical progression of a late-stage PD (LSPD) population over one year follow-up. METHODS: 50 LSPD patients (Schwab and England ADL Scale <50 or Hoehn Yahr Stage >3 in MED ON) underwent an extensive clinical assessment at baseline and after one...


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