10 documents found, page 1 of 1
Recomendações do Grupo Português do Mieloma Múltiplo para Tratamento do Mieloma...
João, Cristina; Bergantim, Rui; Santos, Joana; Afonso, Celina; Bernardo, Paulo; Coelho, Henrique; Costa, Carlos; Esteves, Graça; Freitas, José GuilhermeThe treatment of multiple myeloma has profoundly changed with the introduction of several innovative therapies. The optimization of therapeutic sequencing through the combined use of the various drugs developed in recent years and the attention given to the characteristics of patients have allowed the reduction of toxicities and increased survival and quality of life of patients with multiple myeloma. These tre...
3′Nucleotidase/nuclease is required for Leishmania infantum clinical isolate su...
Carniellie, Juliana; Dave, Anuja; Romano, Audrey; Forrester, Sarah; Faria, Pedro; Renata, Monti-Rocha,; Costa, Carlos; Dietze, R; Graham, IanSummary Background Miltefosine treatment failure in visceral leishmaniasis in Brazil has been associated with deletion of the miltefosine susceptibility locus (MSL) in Leishmania infantum. The MSL comprises four genes, 3′ -nucleotidase/nucleases (NUC1 and NUC2); helicase-like protein (HLP); and 3,2-trans-enoyl-CoA isomerase (TEI). Methods In this study CRISPR-Cas9 was used to either epitope tag or delete NUC1, ...
The perception of population and health professionals regarding the National Im...
Tilman, Carlos; Martins, João Soares; Mausiry, Manuel; Cunha, Mateus; Freitas, Maria Graça; Costa, Carlos
Indicadores de qualidade para avaliar os cuidados clínicos prestados a doentes ...
Catumbela, Emanuel; Santos, Cristina; Freitas, Alberto; Costa, Carlos; Sarmento, António; da Costa Pereira, AltamiroIntroduction: After conducting a systematic review of quality indicators for assessing HIV/AIDS clinical care, we aimed to assess the clinical relevance and practice utility of those indicators from the point of view of HIV/AIDS physician experts. Material and Methods: This is an observational, cross-sectional study, in which we selected, by convenience, physicians who work in an Infectious Disease Department o...
Definition of a core set of quality indicators for the assessment of HIV/AIDS c...
Catumbela, E; Certal, V; Freitas, A; Costa, Carlos; Sarmento, A; Pereira, A
A integração vertical de cuidados de saúde
Santana, Rui; Costa, Carlos
Financiamento por capitação ajustada pelo risco
Costa, Carlos; Santana, Rui; Boto, Paulo
A importância do apuramento de custos por doente
Costa, Carlos; Santana, Rui; Lopes, Sílvia; Barriga, N
Diagnosis Related Groups e Disease Staging
Costa, Carlos; Lopes, Sílvia; Santana, Rui
Variação na mortalidade e na demora média do internamento por dia de admissão e...
Lopes, Sílvia; Costa, Carlos; Boto, Paulo