9 documents found, page 1 of 1

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Production of an extract rich in alpha-tomatine from green tomatoes by subcriti...

Faria-Silva, Catarina; Pedras, Bruno; Costa, Nuno; Carvalheiro, Manuela; Simões, Sandra; Simões, Pedro

Research Institute for Medicines\u2014iMed.ULisboa is funded by FCT through project UID 04138. Publisher Copyright: © 2025 The Authors.; Green tomatoes, a by-product of agro-food industry, are rich in the glycoalkaloid alpha-tomatine. This compound presents health benefits including anti-inflammatory and fungicide properties. Subcritical water extraction (SWE), a green and sustainable process, was used to obtai...


Hydroxytyrosol recovery from olive pomace

Romeu, Maria F. C.; Bernardo, Jorge; Daniel, Carla I.; Costa, Nuno; Crespo, João G.; Silva Pinto, Luís; Nunes da Ponte, Manuel; Nunes, Ana V. M.

Open access funding provided by FCT|FCCN (b-on). P2020—A2020 Projeto no. 023752—“C8H10O3—Hidroxitirosol em novos produtos funcionais focados na prevenção de doenças cardiovasculares e inflamatórias”, of the Programa Operacional Regional Alentejo—Alentejo 2020 (ALT20-03-0247-FEDER-023752) and Associate Laboratory for Green Chemistry (LAQV) Publisher Copyright: © 2023, The Author(s).; In this work, pilot-scale na...


Assessing the resilience of optimal solutions in multiobjective problems

Costa, Nuno; Lourenço, João

Publisher Copyright: © 2023 The Authors; Processes and products are multidimensional so researchers and practitioners have to solve problems with multiple objectives frequently. These problems have, in general, responses in conflict so they do not have a unique solution. Different approaches have been proposed in the literature to solve these problems, but many of them, including the popular desirability functi...


Development of affinity polymeric particles for the removal of 4-dimethylaminop...

Viveiros, Raquel; Pinto, José J.; Costa, Nuno; Heggie, William; Casimiro, Teresa

Funding Information: The Associate Laboratory for Green Chemistry for Green Chemistry - Clean Technologies and Processes - LAQV is financed by national funds from FCT/MCTES and co-financed by the ERDF under the PT2020 Partnership Agreement ( POCI-01–0145-FEDER – 007265 ). Publisher Copyright: © 2023; Polymeric particles with affinity for 4-dimethylaminipyridine (DMAP) were developed by molecular imprinting usin...


Process and Product Optimization Using Game Theory

Costa, Nuno; Lourenço, João

Publisher Copyright: © 2023 ACM.; Game Theory has not been explored so far in multi-objective optimization problems developed in the Response Surface Methodology framework, though optimization of multiple characteristics of process and product is a usual problem faced by practitioners in (non)manufacturing environments. In this paper the Stackelberg's technique complemented with a Factors Scaling tool is propos...


Modified Atmosphere Packaging (MAP) for Seaweed Conservation

Moreira-Leite, Bruno; Antunes, Rafael; Cotas, João; Martins, Nuno; Costa, Nuno; Noronha, João P.; Mata, Paulina; Diniz, Mário

This research was funded by the project “Alga4Food” (MAR-01.03.01-FEAMP-0016) which is funded by the European Maritime and Fisheries Fund (EMFF) and co-funded by the Operational Program MAR2020 in the field of Sustainable Development of Aquaculture in the domains of Innovation, Advice and Productive Investment—Innovation and Knowledge Action. Publisher Copyright: © 2023 by the authors.; Conventional conservatio...


Bi-Objective Optimization Problems—A Game Theory Perspective to Improve Process...

Costa, Nuno; Lourenço, João

Publisher Copyright: © 2022 by the authors. This research received no external funding.; Cost-effective manufacturing processes or products are no longer the only requirements for business sustainability. An approach based on Game Theory is suggested to find solutions for bi-objective problems. In particular, Stackelberg’s technique is employed and complemented with the Factors Scaling tool to help the users in...


Transarterial Embolization of Iatrogenic Cystic Artery Pseudoaneurysm

Proença, Ana Luísa; Veloso Gomes, Filipe; Costa, Nuno; Bilhim, Tiago; Luz, José Hugo; Coimbra, Élia

Cystic artery pseudoaneurysm (CAP) is a rare entity most often resulting from inflammatory conditions (acute cholecystitis or pancreatitis) or iatrogenic trauma (cholecystectomy). We report the case of a 73-year-old female who presented with abdominal pain and gastrointestinal bleeding after an episode of acute cholecystitis and endoscopic retrograde cholangiopancreatography for choledocolithiasis removal. Comp...


Extending NoHR for OWL 2 QL

Costa, Nuno; Knorr, Matthias; Leite, João

Partially supported by Fundação para a Ciência e a Tecnologia under project PTDC/EIA-CCO/121823/2010 and strategic project PEst/UID/CEC/04516/2013. M. Knorr was also supported by grant SFRH/BPD/86970/2012.; The Protégé plug-in NoHR allows the user to combine an OWL 2 EL ontology with a set of nonmonotonic (logic programming) rules - suitable, e.g., to express defaults and exceptions - and query the combined kno...


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