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Direct tissue-sensing reprograms TLR4+ Tfh-like cells inflammatory profile in t...

Amaral-Silva, Daniela; Gonçalves, Rute; Torrão, Rita C.; Torres, Rita; Falcão, Sandra; Gonçalves, Maria João; Araújo, Maria Paula; Martins, Maria José

Funding Information: We thank Cláudia Andrade for technical support and Juliana Gonçalves for testing samples for SARS-CoV-2 exposure. We are extremely grateful to all the participants of the study and to the whole rheumatology department at Hospital Egas Moniz that made this study possible. This work was supported by Fundação para a Ciência e Tecnologia (FCT) PTDC/MEC-REU/29520/2017, by iNOVA4Health UID/Multi/...


Rheuma SPACE - Standard Practice Aiming Clinical Excellence

Macieira, Carla; Cunha-Miranda, L.; Nero, P.; Laires, P.; Bogas, M.; Farinha, S.; Freitas, I; Lucas, P.; Sousa, J.; Narciso, L.; Mateus, E.


The Portuguese Severe Asthma Registry

Sá-Sousa, Ana; Fonseca, João Almeida; Pereira, Ana Margarida; Ferreira, Ana; Arrobas, Ana; Mendes, Ana; Drummond, Marta; Videira, Wanda; Costa, Tiago

The Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...


Ozonoterapia na Osteoartrose do Joelho

Costa, Tiago; Rodrigues-Manica, Santiago; Lopes, Carina; Gomes, João; Marona, José; Falcão, Sandra; Branco, Jaime

INTRODUCTION: The aim of this study was to conduct a systematic review in order to examine the effectiveness of ozone therapy on knee osteoarthritis. The objectives were to evaluate the effect over time of ozone therapy in terms of knee pain, functional improvement and radiographic progression. MATERIAL AND METHODS: A search was carried out on PubMed, Embase, Cochrane Library, Scopus and Web of Science database...


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