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Posterior reversible encephalopathy syndrome and digital gangrene in a patient ...

Martins, Patrícia; Valido, Ana; Melo, Ana Teresa; Santareno, Sofia; Sousa, Rita; Inácio, João R.; Oliveira-Ramos, Filipa; Ponte, Cristina; Romeu, José

Granulomatosis with Polyangiitis (GPA) is an antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis(AAV), classically associated with the presence of proteinase 3 (PR3)-ANCA. GPA has a wide range of clinical manifestations, with multiorgan involvement, particularly upper and lower respiratory tract, and kidneys. One of itsrarest manifestationsis digital ischemia or gangrene that accounts for <1% of ca...


Rheumatology practice amidst the COVID-19 pandemic : a pragmatic view

Romão, Vasco C.; Cordeiro, Inês; Macieira, Carla; Oliveira-Ramos, Filipa; Romeu, José; Rosa, Carlos Miranda; Saavedra, Maria João; Saraiva, Fernando

The coronavirus disease 2019 (COVID-19) pandemic has come with many challenges for healthcare providers and patients alike. In addition to the direct burden it has placed on societies and health systems, it had a significant impact in the care of patients with chronic diseases, as healthcare resources were deployed to fight the crisis, and major travel and social restrictions were adopted. In the field of rheum...


Genetic predictors of poor prognosis in Portuguese patients with Juvenile Idiop...

Mourão, Ana; Santos, Maria; Mendonça, Sílvia; Oliveira-Ramos, Filipa; Salgado, Manuel; Estanqueiro, Paula; Melo-Gomes, José; Martins, Fernando

Introduction: This study aimed to assess the genetic determinants of poor outcome in Portuguese patients with juvenile idiopathic arthritis (JIA). Methods: Our study was conducted in Reuma.pt, the Rheumatic Diseases Portuguese Register, which includes patients with JIA. We collected prospectively patient and disease characteristics and a blood sample for DNA analysis. Poor prognosis was defined as CHAQ/HAQ >0.7...


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