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Psychometric properties of the portuguese version of the chronic urticaria qual...

Ferreira, Pedro L.; Gonçalo, Margarida; Ferreira, José Alberto; Costa, Ana Célia; Todo-Bom, Ana; Abreu, Cristina Lopes; Travassos, Ana Rita

Background: Chronic urticaria is defined as the appearance of urticarial lesions and/or angioedema during a period of more than six weeks. We aimed at developing the Portuguese version of the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) and at testing its reliability and the content, construct and criterion validity. Methods: The forward-backward approach to a linguistic equivalence was followed, a...


Chronic Urticaria in the Real-Life Clinical Practice Setting in Portugal: Basel...

Costa, Ana Célia; Rosmaninho, Isabel; Guilherme, Arminda; Ferreira, José; Antunes, Joana; Pina, Ana; Prates, Sara; Marques, João Gaspar

Introduction: There is a paucity of information regarding chronic urticaria patients’ care in a real-world setting. The objective of this study was to report and evaluate the baseline characteristics of Portuguese chronic urticaria patients refractory to H1-antihistamines included in the AWARE study. Material and Methods: This is a non-interventional cohort study. Adult patients with a diagnosis of chronic urti...

Date: 2019   |   Origin: Acta Médica Portuguesa

Chronic Urticaria – From Diagnose to Treatment

Costa, Ana Célia; Campina, Sofia; Andrade, Pedro; Filipe, Paulo; Guilherme, Arminda; Gonçalo, Margarida

Around 20% of the population suffers at least one urticaria episode, with 0.5 to 1% suffering from chronic urticaria. This disease has a mean duration of 1 to 5 years, and it has a higher incidence in women between 20 and 40 years old. Due to the publication in 2014 of the European guidelines for the management of urticaria, the authors performed a revision covering different aspects of chronic urticaria. Chron...


SUCCESSFUL USE OF OMALIZUMAB IN A PATIENT WITH H1- ANTIHISTAMINE-REFRACTORY CHR...

Silva, Pedro Morais; Mendes, Ana; Costa, Ana Célia; Barbosa, Manuel Pereira

Chronic urticaria (CU) is characterized by an evanescent, itchy wheal and flare reaction that does not resolve completely after 6 weeks. It is a relatively frequent disease that causes significant morbidity. Its therapy with drugs other than H1-antihistamines has not yet been exhaustively studied, but recently some promising treatment options have been described. We describe a case of severe, corticosteroid-dep...


OMALIZUMAB IN SEVERE ATOPIC DERMATITIS

Luz, Sofia; Silva, Pedro; Costa, Ana Célia; Spínola Santos, Amélia; Pedro, Elisa; Pereira Barbosa, Manuel

We present the cases of two young females with severe atopic dermatitis, treated with anti-histamines, topical corticosteroids, high-dose systemic corticosteroids bursts and/or oral cyclosporine, without significant improvement and worsening with tapering of corticosteroids and/or cyclosporine. Several therapeutical adjustments were made without success before starting treatment with subcutaneous omalizumab. Th...


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