12 documents found, page 1 of 2

Editorial: Bacteriophages and their lytic enzymes as alternative antibacterial ...

Editorial on the Research Topic Bacteriophages and Their Lytic Enzymes as Alternative Antibacterial Therapies in the Age of Antibiotic Resistance

Corrigendum to "Ability of phages to infect Acinetobacter calcoaceticus-Acineto...

In Oliveira et al. (2017), the authors would like to inform readers of the following funding information error on page 5072, under Acknowledgements section: This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, COMPETE 2020 (POCI-01-0145-FEDER-006684) and the Project PTDC/BBB-BSS/6471/2014 (POCI-01-0145-FEDER-0...

Author Correction: Efficacy and safety assessment of two enterococci phages in ...

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Erratum for Oliveira et al., "Functional Analysis and Antivirulence Properties ...

Volume 93, no. 4, e01163-18, 2019, https://doi.org/10.1128/JVI.01163-18. Page 14, Acknowledgments, line 4: (POCI-01-0145-FEDER-016678) should read (POCI-01-0145-FEDER-016643).

Proteasome inhibition prevents cell death induced by the chemotherapeutic agent...

Cisplatin is a highly effective chemotherapeutic drug acting as a DNA-damaging agent that induces apoptosis of rapidly proliferating cells. Unfortunately, cellular resistance still occurs. Mutations in p53 in a large fraction of tumor cells contribute to defects in apoptotic pathways and drug resistance. To uncover new strategies to eliminate tumors through a p53-independent pathway, we established a simplified...

Functional analysis and antivirulence properties of a new depolymerase from a m...

Acinetobacter baumannii is an important pathogen causative of healthcare-associated infections and is able to rapidly develop resistance to all known antibiotics including colistin. As an alternative therapeutic agent, we have isolated a novel myovirus (vB_AbM_B9) which specifically infects and makes lysis from without in strains of the K45 and K30 capsule type, respectively. Phage B9 has a genome of 93,641 bp ...

Phage therapy: going temperate?

Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity to mediate transfer of genes between bacteria by specialized transduction â an event that may increase bacterial virulence, for example, by promoting antibiotic resistance. Now, advances in sequencing technologies and synthetic biology are providing new o...

Genomic analysis of Acinetobacter baumannii prophages reveals remarkable divers...

[Abstract] Bacterial genomics has revealed substantial amounts of prophage DNA in bacterial genomes. This integrated viral DNA has been shown to play important roles in the evolution of bacterial pathogenicity. Acinetobacter baumannii has shown a fast progression as a nosocomial multi-resistant pathogen in recent years, and is now considered one of the most dangerous microorganisms in hospital environments. The...

Biofilm phenotype potentiates virulence transduction in Acinetobacter baumannii

3rd International Hands-On Phage Biotechnology Course

[Excerpt] It is my great pleasure to welcome you to the 3rd International hands-on PHAGE BIOTECHNOLOGY course. This course is organized by the Bacteriophage Biotechnology Group at the University of Minho every two years since 2013. During the last 6 years phage biotechnology has witnessed many scientific advances, and new emerging tools are having a great contribution to the field. The three full days of hands-...