4 documents found, page 1 of 1
Intestinal inflammatory and redox responses to the perioperative administration...
Costa, Beatriz Pinto; Gonçalves, Ana Cristina; Abrantes, Ana M.; Matafome, Paulo N.; Seiça, Raquel; Ribeiro, Ana Bela Sarmento; Botelho, Maria FilomenaPurpose: To investigate the inflammatory and redox responses to teduglutide on an animal model of laparotomy and intestinal anastomosis. Methods: Wistar rats (n=62) were allocated into four groups: “Ileal Resection and Anastomosis” vs. “Laparotomy”, each one split into “Postoperative Teduglutide Administration” vs. “No Treatment”; and euthanized at the third or the seventh day. Ileal and blood samples were reco...
Glutaminemia prognostic significance in critical surgical patients - An analysi...
Costa, Beatriz Pinto; Martins, Paulo; Veríssimo, Carla; Simões, Marta; Tomé, Marisa; Grazina, Manuela; Pimentel, Jorge; Sousa, Francisco CastroBackground: Glutamine depletion is common in the critically-ill patients. Glutaminemia lower than 420 μmol/l has been considered as an independent predictive factor of mortality, but the indications for exogenous glutamine supplementation remain controversial. This study intends to determine the glutaminemia profi le in critical surgical patients and to investigate its correlation with the severity indexes and ...
Intestinal dysfunction in the critical trauma patients - An early and frequent ...
Costa, Beatriz Pinto; Martins, Paulo; Veríssimo, Carla; Simões, Marta; Tomé, Marisa; Grazina, Manuela; Pimentel, Jorge; Sousa, Francisco CastroBackground: Small-bowel dysfunction exerts a relevant prognostic impact in the critically ill patients. Citrullinemia has been used in the evaluation of the intestinal function and it is considered an objective parameter of the functional enterocyte mass. Present study proposes to determine the intestinal dysfunction prevalence and the citrullinemia kinetic profi le in severe trauma patients and to investigate ...
Evolution of nutritional status and body composition after major elective surgery
Costa, Beatriz Pinto; Miranda, Andreia; Serôdio, Marco; Fernandes, Miguel; Sousa, F. CastroIntroduction: Despite recognition of its high prevalence and adverse clinical impact, malnutrition remains undervalued and often aggravates during the hospital stay. Objective: To characterize the progression of nutritional status and body composition in the early postoperative period of major elective surgery and to correlate results with the clinical evolution. Material and methods: Prospective study includin...