2 documents found, page 1 of 1
Imipramine reverses depressive-like parameters in pneumococcal meningitis survi...
Vilela, Márcia Carvalho; Barichello, Tatiana; Milioli, Graziele; Generoso, Jaqueline S.; Cipriano, Andreza L.; Costa, Caroline S.; Moreira, Ana PaulaPneumococcal meningitis is a severe infectious disease of the central nervous system, associated with acute inflammation and might cause damage to the host, such as deafness, blindness, seizure, and learning deficits. However, infectious diseases can play a significant role in the etiology of neuropsychiatric disturbances. In this context, we evaluated depressive-like parameters; corticosterone and ACTH levels ...
Brain–blood barrier breakdown and pro-inflammatory mediators in neonate rats su...
Barichello, Tatiana; Fagundes, Glauco D.; Generoso, Jaqueline S.; Moreira, Ana Paula; Costa, Caroline S.; Zanatta, Jessiele R.; Simões, Lutiana R.Neonatal meningitis is an illness characterized by inflammation of the meninges and occurring within the birth and the first 28 days of life. Invasive infection by Streptococcus pneumoniae, meningitis and sepsis, in neonate is associated with prolonged rupture of membranes; maternal colonization/illness, prematurity, high mortality and 50% of cases have some form of disability. For this purpose, we measured bra...