Clostridioides difficile BI/NAP1/ribotype 027 is an epidemic hypervirulent strain found worldwide, including in Latin America. We examined the genomes and exoproteomes of two multilocus sequence type (MLST) clade 2 C. difficile strains considered hypervirulent: ICC‑45 (ribotype SLO231/UK[CE]821), isolated in Brazil, and NAP1/027/ST01 (LIBA5756), isolated during a 2010 outbreak in Costa Rica. C. difficile isolat...
Clostridioides difficile is a strictly anaerobic, spore-forming, toxin-producing Gram positive bacillus which is recognized to be the major cause of nosocomial diarrhea associated with antibiotic therapy. The aim of this study was to characterize a new strain of C. difficile (ICC45) isolated from a patient in a cancer hospital in Fortaleza and compare with the strains ATCC 700057 (non-toxigenic) and NAP1/027 (R...
Clostridium difficile is a strictly anaerobic, spore-forming, toxin-producing Gram positive bacillus. Currently, it is the main cause of nosocomial diarrhea associated with antibiotic use. Cancer patients are a major risk group for C. difficile infection (CDI), since the use of chemotherapeutic agents can alter the intestinal mucosa. Furthermore, these patients are often immunosuppressed and often use broad spe...
Groundwater, one of the most used fonts in the world for human consumption, has the potential capacity of transmission of diseases caused by pathogenic microorganisms from human and animal feces, or by chemicals in concentrations beyond the standards allowed by Ordinance 2914/2011/MS, making it essential verification and monitoring of its potability. This work aims to evaluate the microbiological and chemical q...