3 documents found, page 1 of 1
Transforming second-generation ethanol production waste into sustainable enzyma...
Polesso, Camila Borges; Fontana, Roselei Claudete; Costa, Cristiana C.; Fernandes, Bruno; Matamá, Maria Teresa Gonçalves Macedo; Cavaco-Paulo, ArturAgro-industrial residues were used as a successful, cheap and renewable substrate, capable of increasing activity of ligninolytic enzymes for further use in melanin degradation assays to develop inputs for the treatment of skin hyperpigmentation. The analysis of melanin degradation was performed in a quantitative and qualitative way. The enzymatic crude broth extract, rich in laccases, produced by Marasmiellus ...
Mapping hair follicle-targeted delivery by particle systems: what has science a...
Costa, Cristiana C.; Cavaco-Paulo, Artur; Matamá, TeresaThe importance of the hair follicle in the process of cutaneous drug penetration has been established since this skin appendage was recognized as an entry point for topically applied substances. A comprehensive review on the hair follicle as a target per se is here provided, exploring the current knowledge on both targeted regions and delivery systems that take advantage of this permeation route. The follicular...
Composition for hair follicle modulation, methods and uses thereof
Cavaco-Paulo, Artur; Matamá, Teresa; Costa, Cristiana C.; Fernandes, Bruno PachecoThe present disclosure relates to a composition for use in the hair follicle modulation comprising a bioactive agent a thickener agent; a preservative; and a denaturing alcohol. The present disclosure also comprises a pharmaceutical composition for use in the prevention, therapy or treatment of abnormal defective production of melanin, comprising a bioactive agent selected from dipyridamole, dipyridamole salt, ...