3 documents found, page 1 of 1
Pharyngolaryngeal reflux disease - Can symptoms predict endoscopic findings?
Costa, Isabel; Sousa, Mariana; Costa, Dalila; Lima, António; Rodrigues, Berta; Dias, LuísAim: to correlate the severity of symptoms with pharyngolaryngeal endoscopic findings in individuals diagnosed with pharyngolaryngeal reflux disease (PLRD). Design of the study: unicentric, observational and prospective study. Material and Methods: 109 adults attended the ENT and Gastroenterology consultation at Hospital de Braga between April and October 2019 with suspected symptoms of PLRD. Through the applic...
Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Def...
Hamesch, Karim; Mandorfer, Mattias; Pereira, Vítor Magno; Moeller, Linda S.; Pons, Monica; Dolman, Grace E.; Reichert, Matthias C.BACKGROUND & AIMS: Alpha-1 antitrypsin deficiency (AATD) is among the most common genetic disorders. Severe AATD is caused by a homozygous mutation in the SERPINA1 gene that encodes the Glu342Lys substitution (called the Pi*Z mutation, Pi*ZZ genotype). Pi*ZZ carriers may develop lung and liver diseases. Mutation- associated lung disorders have been well studied, but less is known about the effects in liver. We ...
Influence of seasons and land-use practices on soil microbial activity and meta...
Costa, Dalila; Freitas, H.; Sousa, J. P.The “Montado ecosystem” is important both economically and ecologically; this ecosystem is dominated by cork and holm oak trees (Quercus suber L. and Quercus rotundifolia Lam. respectively) combined with a rotation of crops/fallow/pastures. Diverse management strategies, deviating from the sustainable use of the ecosystem, have been implemented, from which arise some extreme situations of over-use or abandonmen...