3 documents found, page 1 of 1
Anti-leishmania activity of extract and fractions from the stem and leaf of Mon...
Faria, Lara Vinha; Brígido, Heliton Patrick Cordovil; Bentaberry-Rosa, Alexandre Augusto; Correa-Barbosa, Juliana; Silva-Silva, João VictorThis study aimed to evaluate the anti-leishmania activity of extracts and fractions from stem and leaf of Montrichardia linifera against Leishmania amazonensis. The stem (EES) and leaf (EEL) extracts were obtained by maceration of powders with 96º GL alcohol. The extracts were subjected to exhaustive extraction using a reflux system and solvents of increasing polarity, obtaining 4 fractions for each extract: he...
Antileishmanial Activity of Handroanthus serratifolius (Vahl) S. Grose (Bignoni...
Costa, Erica Vanessa Souza; Brígido, Heliton Patrick Cordovil; Silva, João Victor da Silva e; Coelho-Ferreira, Marlia Regina; Brandão, Geraldo CélioEste estudo teve como objetivo avaliar a atividade leishmanicida do extrato etanólico, frações e substância isolada de Handroanthus serratifolius contra Leishmania amazonensis. Além disso, essa atividade estava relacionada à citotoxicidade e o índice de seletividade O extrato etanólico foi obtido por maceração do pó do caule e o extrato foi submetido ao fracionamento em coluna cromatogrica. O lapachol foi obtid...
Antileishmanial activity of Handroanthus serratifolius (Vahl) S. Grose (Bignoni...
Costa, Erica Vanessa Souza; Brígido, Heliton Patrick Cordovil; Silva, João Victor da Silva e; Ferreira, Marlia Regina Coelho; Brandão, Geraldo CélioThis study aimed to evaluate the leishmanicidal activity of ethanol extract, fractions, and isolated substance from Handroanthus serratifolius against Leishmania amazonensis. Furthermore, this activity was related to cytotoxicity, and the selectivity index was determined.The ethanol extract was obtained by maceration of the stem powder, and the extract was subjected to fractionation on chromatographic column. T...