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Randomized clinical study of injectable dextrin-based hydrogel as a carrier of ...

Machado, Alexandra; Pereira, Isabel; Costa, Filomena; Brandão, Ana; Pereira, José Eduardo; Maurício, Ana Colette; Santos, José Domingos; Amaro, Inês

Objectives This study aimed to improve the performance and mode of administration of a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), by association with a dextrin-based hydrogel, DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone. Methods Twelve participants requiring pre-molar tooth extraction and implant placement were enrolled in this study. BL® g...


Randomized clinical study of injectable dextrin-based hydrogel as a carrier of ...

Machado, Alexandra; Pereira, Isabel; Costa, Filomena; Brandão, Ana; Pereira, José Eduardo; Maurício, Ana Colette; Santos, José Domingos; Amaro, Inês

This study aimed to improve the performance and mode of administration of a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), by association with a dextrin-based hydrogel, DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone.


Recovery of rare earth elements from wastewater towards a circular economy

Barros, Óscar; Costa, Lara; Costa, Filomena; Lago, Ana Elisa Marques; Rocha, Verónica Patrícia Moreira; Vipotnik, Ziva

The use of rare earth elements is a growing trend in diverse industrial activities, leading to the need for eco-friendly approaches to their efficient recovery and reuse. The aim of this work is the development of an environmentally friendly and competitive technology for the recovery of those elements from wastewater. Kinetic and equilibria batch assays were performed with zeolite, with and without bacterial b...


Pilot-scale sorption studies of diethylketone in the presence of Cd2+ and Ni2+

Costa, Filomena; Tavares, T.

The pH effect on the sorption capacity of vermiculite towards cadmium and nickel was tested in batch systems and it was shown that the sorption percentages increase with increasing the mass of vermiculite and with increasing the initial pH. Maximum sorption percentages were obtained for a pH of 8 and 4 g of vermiculite (86.5 % for Cd2+ and 86.1 % for Ni2+, for solutions with 100 mg/L of metal). As a consequence...


Diethylketone and Cd pilot-scale biosorption by a biofilm supported on vermiculite

Costa, Filomena; Tavares, T.

The pilot-scale assays conducted with a joint bacteria-clay system Streptococcus equisimilis (S. equisimilis) biofilm supported on vermiculitewere conducted in a close loop reactor aiming the decontamination of large volumes of binary aqueous solutions containing diethylketone and Cd2+. The joint system employed proved to be able to simultaneously biodegrade diethylketone and biosorb Cd2+: the removal (biodegra...


Permeable biosorbent barrier for wastewater remediation

Silva, B; Tuuguu, E.; Costa, Filomena; Rocha, Verónica; Lago, A.; Tavares, Teresa

Chromium is one of the heavy metals that significantly affect water quality in Mongolia. The present study is focused on the remediation of surface water contaminated with chromium (III) by a permeable barrier in order to prevent sediment pollution. The adsorption capacity of the selected materials (13X zeolite and vermiculite) was investigated at different sorbent dosages, pH and initial Cr(III) concentration....


Sorption studies of diethylketone in the presence of Al3+, Cd2+, Ni2+ and Mn2+,...

Costa, Filomena; Tavares, Teresa

The toxic effects of diethylketone (DEK) in aqueous solution with different concentrations of Al3+, Cd2+, Ni2+ and Mn2+ were evaluated at lab-scale. It was established that Streptococcus equisimilis is able to efficiently remove DEK with different concentrations with heavy metals. It was proved that this joint-system has excellent capacity to biodegrade high concentrations of DEK in the presence of Al3+, Cd2+, ...


Biofilm Bioprocesses

Costa, Filomena; Silva, Bruna; Tavares, T.

This text reviews current knowledge on biofilm formation, properties, and specific characteristics and relates them to bioprocesses with industrial interest in the environmental, fine-chemistry, and alternative energy fields. From the basics to the most recent evaluations of biofilm bioprocesses, going through the technological aspects of engineered systems, a thorough presentation is made of microorganisms, me...


Bioremoval of Ni and Cd in the presence of diethylketone by fungi and by bacter...

Costa, Filomena; Tavares, T.

Two fungi (Alternaria sp. and Penicillium sp.) and one gram-positive bacterium (Streptococcus equisimilis) were used to remove Ni and Cd from aqueous solutions in the presence of diethylketone. Individual toxicity assays were performed at an initial stage to evaluate the xenobiotic impact of the initial concentration of those metals on the growth of the microorganisms and allowed to infer that the growth of S. ...


Biosorption of nickel and cadmium in the presence of diethylketone by a Strepto...

Costa, Filomena; Tavares, T.

A Streptococcus equisimilis biofilm supported on clays was used to decontaminate aqueous solutions containing diethylketone (DEK), nickel and/or cadmium, in a batch mode. The interaction between the sorbent matrices and the different sorbates, individually and in binary combinations, was evaluated. It was demonstrated that the growth of S. equisimilis is negatively affected by concentrations higher than 80 mg l...


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