3 documents found, page 1 of 1
Injectable hydrogels for the delivery of nanomaterials for cancer combinatorial...
Lima-Sousa, Rita; Alves, Cátia; Melo, Bruna L.; Costa, Francisco J. P.; Nave, Micaela; Moreira, André F.; Mendonça, António; Correia, I.J.Progress in the nanotechnology field has led to the development of a new class of materials capable of producing a temperature increase triggered by near infrared light. These photothermal nanostructures have been extensively explored in the ablation of cancer cells. Nevertheless, the available data in the literature have exposed that systemically administered nanomaterials have a poor tumor-homing capacity, hi...
Simple preparation of POxylated nanomaterials for cancer chemo-PDT/PTT
Nave, Micaela; Costa, Francisco J. P.; Alves, Cátia; Sousa, Rita Lima; Melo, Bruna L.; Correia, I.J.; Diogo, Duarte de MeloNear infrared (NIR) light-responsive nanomaterials hold potential to mediate combinatorial therapies targeting several cancer hallmarks. When irradiated, these nanomaterials produce reactive oxygen species (photodynamic therapy) and/or a temperature increase (photothermal therapy). These events can damage cancer cells and trigger the release of drugs from the nanomaterials’ core. However, engineering nanomateri...
Development of Thiol-Maleimide hydrogels incorporating graphene-based nanomater...
Costa, Francisco J. P.; Nave, Micaela; Sousa, Rita Lima; Alves, Cátia; Melo, Bruna L.; Correia, I.J.; Diogo, Duarte de MeloNano-sized materials have been widely explored in the biomedicine field, especially due to their ability to encapsulate drugs intended to be delivered to cancer cells. However, systemically administered nanomaterials face several barriers that can hinder their tumor-homing capacity. In this way, researchers are now focusing their efforts in developing technologies that can deliver the nanoparticles directly int...