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The inflammation-related biomarker CXCR7 independently predicts patient outcome...

Santos, PB; Lobo, J; Félix, A; Silva, F; Manso, RT; Costa, J, et al.

INTRODUCTION: The influence of inflammation on prostate tumor carcinogenesis is currently much better known than with its role in prostate cancer (CaP) progression. We evaluated the prognostic value of epigenetic (HDAC1, HDAC4, H3Ac) and inflammation-related (CXCR4, CXCR7, CXCL12) biomarkers immunoexpression, in radical prostatectomy specimens, from 2 cohorts of CaP patients with long term follow-up. MATERIALS ...


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