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Aflatoxins and ochratoxin A contamination during Merkén Pepper Powder productio...

Costa, Jéssica; Santos, Carla Isabel Arcanjo; Soares, Célia Maria Gonçalves; Lima, Nelson; Santos, Cledir

Berry fruits of Capsicum annuum L. cv. "Cacho de Cabra are used for the manufacture of a traditional pepper powder known as Merkén, which is a Chilean spicy widely consumed at national level in Chile and also exported to different countries. Merkén contamination with Aflatoxins (AFs) and Ochratoxin A (OTA) is a main concerning for local producers and national and worldwide consumers. In the present study, AFs a...


Filamentous fungi isolated and identified from Antarctic soil (Fildes Bay, Anta...

Gallardo, V.; Sepúlveda, M.; Cayún, Y.; Barría, E.; Mella, M.; Costa, Jéssica; Dias, N.; Lima, Nelson; Cornejo, P.; Santos, Cledir

Purpose: Antarctica is a unique place with extreme environmental conditions, including low temperature, high solar radiation, low nutrient availability and strong winds. This different environment represents a gateway to studies on the taxonomy, ecology, and biotechnology of organisms under extreme conditions. Fungi are ubiquitous and diverse organisms in Antarctica and have been described as growing in differe...



Antifungal potential of capsaicinoids and capsinoids from the capsicum genus fo...

Costa, Jéssica; Sepúlveda, Marcela; Gallardo, Víctor; Cayún, Yasna; Santander, Christian; Ruíz, Antonieta; Reyes, Marjorie; Santos, Carla Isabel Arcanjo

Opportunistic pathogenic fungi arise in agricultural crops as well as in surrounding human daily life. The recent increase in antifungal-resistant strains has created the need for new effective antifungals, particularly those based on plant secondary metabolites, such as capsaicinoids and capsinoids produced by <i>Capsicum</i> species. The use of such natural compounds is well-aligned with the One Health approa...


Occurrence of aflatoxins and Ochratoxin A during merkén pepper powder productio...

Costa, Jéssica; Santos, Carla Isabel Arcanjo; Soares, Célia Maria Gonçalves; Rodriguez, R.; Lima, Nelson; Santos, Cledir

Berry fruits of Capsicum annuum L. cv. “Cacho de Cabra” are used for the manufacture of a traditional pepper powder known as Merkén. In the present study, aflatoxins (AFs) and ochratoxin A (OTA) contamination in berry fruits of C. annuum was determined at harvest, drying, and smoking stages of Merkén production, in cumin and coriander seeds used as Merkén ingredients, and in the final packaged Merkén produced b...


An overview on possible links between aflatoxin B1 exposure and gallbladder cancer

Costa, Jéssica; Lima, Nelson; Santos, Cledir

Gallbladder cancer (GBC) is one of the most common sites for biliary tract cancers. It has a worldwide distribution being endemic in South America and Southern Asia. These high GBC rates have previously been linked to the determinants of health such as nutrition, genetics, lifestyle, and environment. Exposure to aflatoxin B1 (AFB1), a human carcinogen, is suggested to be involved with GBC development. This work...


COVID-19, Chikungunya, Dengue and Zika diseases: an analytical platform based o...

Costa, Jéssica; Ferreira, Eugénio C.; Santos, Cledir

COVID-19 and arboviruses (ARBOD) epidemics co-occurrence is a great concern. In tropical and subtropical regions, ARBOD diseases such as chikungunya, dengue, and Zika are frequent. In both COVID-19 and ARBOD cases, an accurate diagnosis of infected patients is crucial to promote adequate treatment and isolation measures in COVID-19 cases. Overlap of clinical symptoms and laboratory parameters between COVID-19 a...


Mycotoxin contamination in Capsicum pepper and Merkén: Implications for Human H...

Costa, Jéssica; Lima, Nelson; Santos, Cledir

Mycotoxins are low-molecular-weight secondary metabolites produced by filamentous fungi.


Influence of S. cerevisiae and P. kluyveri as starters on chocolate flavour

Moreira, Igor; Costa, Jéssica; Vilela, Leonardo; Lima, Nelson; Santos, Cledir; Schwan, Rosane

BACKGROUND Fermented cocoa beans (Theobroma cacao L.) is a pivotal raw material for chocolate production. A cocktail yeast applied in the cocoa fermentation process can promote the formation of the pleasant metabolites. Saccharomyces, Pichia, and Hanseniaspora have been widely used in fermentation to improve the final product organoleptic profile. Highlighting that fermentation is a critical point for chocolate...


The impact of overnight orthokeratology on accommodative response in myopic sub...

Pereira-da-Mota, Ana F.; Costa, Jéssica; Amorim-de-Sousa, Ana; González-Méijome, José Manuel; Queirós, A.

This study aimed to evaluate the effects of two months of orthokeratology (OK) treatment in the accommodative response of young adult myopes. Twenty eyes (21.8 ± 1.8 years) were fitted with the Paragon CRT<sup>®</sup> 100 LENS to treat myopia between −1.00 and −2.00 D. Low- and high-contrast visual acuity (LCDVA and HCDVA), central objective refraction, light disturbance (LD), and objective accommodative respon...


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