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Neospora caninum: high susceptibility to the parasite in C57BL/10ScCr mice

Botelho, A. S.; Teixeira, L.; Costa, J. M. Correia da; Faustino, A. M. R.; Castro, António G.; Vilanova, M.

C57BL/10ScCr mice, lack Toll-like receptor 4 and a functional Interleukin-12 receptor. Taking this into account, susceptibility of these mice to Neospora caninum infection was assessed comparatively to that of immunocompetent C57BL/10ScSn mice. C57BL/10ScCr mice inoculated intraperitoneally with 5 x 10(5) N. caninum tachyzoites showed a high Susceptibility to this parasite. All infected C57BL/10ScCr mice were d...


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