The influence of an in-situ acclimatization period of five weeks, seeking the settlement and fidelity of hatchery-reared dusky groupers (Epinephelus marginatus) to the release sites in restocking actions, was tested using acoustic biotelemetry. Eight tagged adult groupers were submitted to the wild conditions in a fish farm cage, while seven remained in the hatchery and tagging location until they were all rele...
In the framework of stock enhancement, field experiments were conducted between March and July 2021 in rocky shores of Central Portugal to test the usefulness of refuges and calcein marking for juvenile sea urchins releases. Individuals with 10–20 mm in test diameter were captured in nature and tagged through immersion in a calcein bath with a concentration of 150 mg L−1, during 48 hr. Artificial shelters were ...
The sea urchin Paracentrotus lividus (Lamarck, 1816) (Echinodermata: Echinoidea) is an important economic resource in Europe, but intense harvesting has led to the collapse of several natural populations. Echinoculture, associated with restocking and stock enhancement practices, is an alternative to this problem. In these procedures, reliable individual identification through tagging is a valuable source of inf...
Marine Protected Areas (MPAs) require effective indicators to assess their performance, in compliance with the goals of relevant national and international commitments. Achieving and prioritizing shortlists of multidisciplinary indicators demands a significant effort from specialists to depict the multiple conservation and socioeconomic interests, and the large complexity of natural systems. The present paper d...
Catálogo da exposição “Áreas Marinhas Protegidas da Costa Sudoeste”.
Áreas Marinhas Protegidas da Costa Sudoeste.
Lung cancer is still the leading cause of cancer death in the world. For this reason, novel approaches for early and more accurate diagnosis are needed. Computer-aided decision (CAD) can be an interesting option for a noninvasive tumour characterisation based on thoracic computed tomography (CT) image analysis. Until now, radiomics have been focused on tumour features analysis, and have not considered the infor...
Background. The tumor immune microenvironment exerts a pivotal influence in tumor initiation and progression. The aim of this study was to analyze the immune context of sporadic and familial adenomatous polyposis (FAP) lesions along the colorectal adenoma–carcinoma sequence (ACS). Methods. We analyzed immune cell counts (CD3+, CD4+, CD8+, Foxp3+, and CD57+), tumor mutation burden (TMB), MHC-I expression and PD-...
Introduction: Cell-free DNA (cfDNA) analysis offers a non-invasive method to identify sensitising and resistance mutations in advanced Non-Small Cell Lung Cancer (NSCLC) patients. Next-generation sequencing (NGS) of circulating free DNA (cfDNA) is a valuable tool for mutations detection and disease' s clonal monitoring. Material and methods: An amplicon-based targeted gene NGS panel was used to analyse 101 plas...
Melanoma is the deadliest form of skin cancer, primarily due to its high metastatic propensity and therapeutic resistance in advanced stages. The frequent inactivation of the p53 tumour suppressor protein in melanomagenesis may predict promising outcomes for p53 activators in melanoma therapy. Herein, we aimed to investigate the antitumor potential of the p53-activating agent SLMP53-2 against melanoma. Two-and ...